Struvite Stones Antibiotic Study

Status Recruiting

Clinical Trial Summary

The aim of this research is to determine an effective antibiotic regimen following definitive surgical therapy of kidney stones caused by bacterial infection (struvite stones).

Clinical Trial Description

Struvite stones or infection stones are a subset of kidney stones that are related to bacterial infection. They only make up 15% of all kidney stones, but account for a much higher percentage of mortality (up to 67%) compared to other stones-due to the infectious component. Treatment is to ensure 100% eradication of the stone with surgery followed by antibiotics to eliminate the infection. Failure to eliminate the bacteria results in the stone growing back quickly. It is unknown how long antibiotics should be administered immediately after surgery-some urologists give 2-4 weeks while others give 2-3 months. We seek to randomize patients to receive 2 weeks of antibiotics or 3 months of antibiotics after surgery to remove all the kidney stones. We will see patients at 3, 6, and 12 months with x-rays and to test their urine for bacterial infections. This is a multi-centre study with participating 12 sites across North America. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02375295
Study type	Interventional
Source	University of British Columbia
Contact	Olga Arsovska
Phone	6048754111
Email	olga.arsovska@ubc.ca
Status	Recruiting
Phase	Phase 4
Start date	March 2015
Completion date	December 2023

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