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Kidney Calculi clinical trials

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NCT ID: NCT05077007 Recruiting - Acute Kidney Injury Clinical Trials

Evaluation of Renal Damage After PCNL and ESWL Using Novel RNA Based Biomarkers

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The study evaluate the damage effect of ESWL and PCNL on kidney tissue by measuring non-coding lnc-RNA profile in urine before and after ESWL and PCNL procedures

NCT ID: NCT05026710 Recruiting - Renal Stone Clinical Trials

Better Lithotripsy and Ureteroscopy Evaluation of Stenting (BLUES)

BLUES
Start date: December 2, 2021
Phase: N/A
Study type: Interventional

This multi-center trial is being completed to compare patient outcomes related to the Imajin silicone stent in comparison to non-silicone polyurethane stents after ureteroscopy. Eligible participants will be enrolled and randomly assigned to receive the Imajin silicone stent or a non-silicone stent. In addition, the participants will complete questionnaires and have follow-up information collected (approximately 60 days after surgery). The trial hypothesizes that a ureteral stent made of silicone, will have superior outcomes when compared to non-silicone stents.

NCT ID: NCT05014178 Recruiting - Clinical trials for Chronic Kidney Disease

Kidney Sodium Functional Imaging

Start date: September 16, 2021
Phase:
Study type: Observational

The corticomedullary gradient is largely responsible for developing the gradients that are needed to concentrate urine (more solutes and less water). The ability of the kidneys to produce concentrated urine is a major determinant of the ability to survive the warm weather. When temperatures are high, we lose water through sweat, and so the kidneys retain water to maintain fluidity in the blood. The maintenance of a sodium (salt) gradient is required for urine concentration because increased medullary sodium concentration increases the reabsorption of water into the kidney, to be redistributed in the blood. The purpose of this study is to know if the corticomedullary gradient is altered in patients across a wide spectrum of kidney disease using sodium Magnetic Resonance Imaging (MRI), a machine that takes pictures and measures the salt content in the kidneys. 23Na kidney MRI, will provide functional MR of the kidney as a non-invasive tool to describe medullary function to improve management of chronic and kidney disease.

NCT ID: NCT05012215 Recruiting - Kidney Stones Clinical Trials

Paravertebral Versus Caudal Block in Pediatric PCNL

Start date: August 19, 2021
Phase: N/A
Study type: Interventional

To compare the efficacy of Ultrasound guided thoracic paravertebral block versus ultrasound guided caudal epidural block in pediatric patients undergoing percutaneous nephrolithotomy

NCT ID: NCT05006937 Recruiting - Kidney Stone Clinical Trials

High Powered Stone Dusting vs. Fragmentation and Basketing at Time of Ureteroscopy

Start date: July 28, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the differences in stone free results, patient side effects, and patient satisfaction between dusting vs. basket extraction for kidney and ureteral stones (a kidney stone located in the tube between the kidney and bladder) 6 mm and greater in size undergoing ureteroscopic treatment. Dusting is when a laser is used to break a stone down into tiny fragments that are able to pass through the urine. Basket extraction is when a small wire basket is used to remove stone fragments.

NCT ID: NCT04997668 Recruiting - Kidney Stone Clinical Trials

Clinical Outcomes and Healthcare Economics of SOLTIVE Compared to Ho:YAG Laser in Urolithiasis

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

To compare intraoperative as well as postoperative outcomes of SOLTIVE Thulium laser compared to Ho:YAG laser for the treatment of urolithiasis. The hypothesis is that utilizing the SOLTIVE Thulium laser for the treatment of urolithiasis will result in a more efficient procedure, with comparable stone free rate to that of Holmium laser and subjective improvement in physician satisfaction.

NCT ID: NCT04937192 Recruiting - Kidney Stone Clinical Trials

SNP-based Prediction of Recurrence Risk in Kidney Stone Patients

Start date: January 1, 2012
Phase:
Study type: Observational

The goal of this study is to gain new knowledge about genetic risk factors that may affect the kidney stone recurrence. The study seeks to understand if different forms of genes result in an increased risk of kidney stone recurrence.

NCT ID: NCT04900688 Recruiting - Kidney Stone Clinical Trials

Prospective Evaluation of the LithoVue Elite Ureteroscope

LVE
Start date: January 16, 2023
Phase: N/A
Study type: Interventional

Flexible ureteroscopy has become the main surgical treatment for kidney stone disease. The procedure uses many types of ureteroscopes (disposable and non-disposable). Currently we are using the LithoVue Single-Use Digital Flexible Ureteroscope. The Health Canada approved LithoVue Elite disposable flexible ureteroscope will now offer novel pressure sensory capacity. In order to evaluate the new ureteroscopy we will be conducting a prospective multi-institution study in order to determine the main features, capacity and abilities of the new scope. We will evaluate the impact of intra renal pressure on pain, quality of life and possible infectious complications.

NCT ID: NCT04869293 Recruiting - Pain Clinical Trials

Lithotripsy and Analgesia With 3D Hypnosis Mask

LAHMA
Start date: April 15, 2021
Phase: N/A
Study type: Interventional

The study is a randomised trial of hypnosis with 3D virtual reality headset (intervention group) versus control group with no hypnosis and no virtual reality headset to compare remifentanil consumption during shock wave lithotripsy.

NCT ID: NCT04856722 Recruiting - Renal Stone Clinical Trials

Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones

Start date: April 5, 2021
Phase: N/A
Study type: Interventional

The optimal management of medium-sized renal stones remains quite challenging and continues to be contested. In the present study, the investigators will compare mini-PNL, RIRS and SWL in the treatment of non- lower pole, medium size, high dense renal stones regarding the stone-free rate, the safety of the procedures, cost, and patients' and surgeon's satisfaction. Eligible patients will be randomly allocated into three equal groups (mini-PNL, RIRS, and SWL). Postoperative, patients will be followed-up by regularly for 3 months. The study parameters will be compared between groups.