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Kidney Calculi clinical trials

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NCT ID: NCT05591716 Recruiting - Kidney Stone Clinical Trials

Evaluation of the Efficacy and Safety of Unimodal Bilateral Flexible Ureteroscopy.

Start date: October 17, 2022
Phase: N/A
Study type: Interventional

This is a prospective controlled study to compare the efficacy and safety of two methods of flexible urethroscopy in patients with urolithiasis, as well as the effect of surgery on quality of life.

NCT ID: NCT05578807 Recruiting - Kidney Calculi Clinical Trials

Total Tubeless Percutaneous Nephrolithotomy Without a Ureteral Catheter

Start date: September 28, 2022
Phase: N/A
Study type: Interventional

Total tubeless Percutaneous nephrolithotomy (PCNL) is a modified surgical method of PCNL surgery, that is, there is no indwelling nephrostomy tube and double-J tube during PCNL surgery. Compared with traditional PCNL surgery, it has the advantages of reducing pain, shortening operation time and reducing operation cost. Since this procedure was first performed in 2004, several randomized clinical studies have verified the safety and efficacy of total tubeless PCNL. Conventional total tubeless PCNL surgery requires the patient to first undergo retrograde transurethral ureteroscopic insertion of the ureteral catheter in the lithotomy position, and then change the patient to the prone position. However, a large number of literature reports and the surgical experience of PCNL in the past 20 years tell the investigators that the reverse insertion of ureteral catheter can cause many recent surgical complications.The study planned to perform the operation in the prone position without reverse insertion of a ureteral catheter in the total tubular PCNL surgery.

NCT ID: NCT05535816 Recruiting - Clinical trials for Ultrasound Therapy; Complications

Accuracy of Ultrasound for Detecting Residual Fragments During RIRS

Start date: March 27, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the accuracy of ultrasound and traditional fluoroscopy to find the residual fragments before retrograde intrarenal surgery is complete. This would ultimately limit the need for radiation exposure and improve the quality of clinical care given to patients and healthcare teams.

NCT ID: NCT05460559 Recruiting - Stone, Kidney Clinical Trials

Endoscopic Combined Intrarenal Surgery Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones:

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to compare outcomes of endoscopic combined intrarenal surgery (ECIRS) with the multi-tract percutaneous nephrolithotomy for management of complex renal stones.

NCT ID: NCT05460247 Recruiting - Clinical trials for Kidney Stone Prevention

Protein Sources Urinary Stone Risk

Start date: October 30, 2022
Phase: N/A
Study type: Interventional

Prior studies have shown that the source of dietary protein can have a significant impact on urinary stone risk. However, whey and plant protein isolates have not been compared. This is an important distinction as protein supplements fortified foods are increasingly popular. Herein, we seek to investigate the effect of different protein supplements, in an otherwise identical diet, on urinary stone risk.

NCT ID: NCT05417568 Recruiting - Kidney Stones Clinical Trials

Oxalate-Driven Host Responses in Kidney Stone Disease

Start date: May 19, 2023
Phase: N/A
Study type: Interventional

This study is looking to understand the role of oxalate on kidney stone development and immunity. This study will enroll healthy participants and participants with calcium oxalate kidney stones (CaOx KS). Participants will be in this study for about 3 weeks, consume controlled diets, and provide blood and urine specimens.

NCT ID: NCT05389995 Recruiting - Kidney Stone Clinical Trials

Potassium Citrate and Crystal Light Lemonade

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

To define the effect of crystal light, potassium citrate, or both on urinary stone risk factors in patients with a history of stone and hypocitraturia/low pH

NCT ID: NCT05384197 Recruiting - Renal Stone Clinical Trials

Enhanced Versus Extended Preoperative Antibiotic Prophylaxis Regimens for Retrograde Intrarenal Surgery in High Infectious Risk Patients

Start date: May 1, 2022
Phase: Phase 3
Study type: Interventional

In the available literature, there is a lack the risk categorization of infectious complications after RIRS with subsequent recommendation as regard to AP in different risk patients. Therefore this study is planning to investigate the optimal protocol for AP prior to RIRS in high-risk population through comparing the enhanced regimen (2days) vs. the extended regimen (7 days) in a randomized controlled trial (RCT).

NCT ID: NCT05379894 Recruiting - Kidney Stone Clinical Trials

Modified Supine vs Prone Position Pnl

Start date: June 1, 2022
Phase:
Study type: Observational

perform a comparative randomized trial comparing the efficacy and safety of percutaneous nephrolithotomy (PCNL) in the prone and modified supine positions in management of complex renal stones

NCT ID: NCT05365477 Recruiting - Nephrolithiasis Clinical Trials

Empiric Versus Selective Prevention Strategies for Kidney Stone Disease

Start date: August 4, 2022
Phase: Phase 4
Study type: Interventional

The aims of this study are to 1) Conduct a randomized clinical trial of selective versus empiric diet plus pharmacologic therapy in high-risk stone formers and 2) Determine adverse effects from, and adherence to selective and empiric strategies.