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Kidney Calculi clinical trials

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NCT ID: NCT02037906 Completed - Renal Stones Clinical Trials

Escalating, Constant and Reduction Energy Output in SWL for Renal Stones

SWL
Start date: January 2014
Phase: N/A
Study type: Interventional

Research Problem: Shock wave lithotripsy (SWL) dramatically changed the management of renal and ureteral calculus disease. In vitro studies suggest that progressive increase in lithotripter energy output voltage could produce the best overall stone comminution in comparison with constant or deescalating energy output. However, it is possible that the beneficial impact of slow rate SWL on comminution of stones and stone free rates has masked any marginal benefits for energy output escalation. The Escalating SW method adds the benefit of less renal tissue injury. Research Significance:The present study will signifies and evaluates the stone free rates of three groups of patients with renal stones treated with different SWL energy outputs (Escalating, Constant and Reduction energy output). Research Objectives: The aim of this research project is to study the effect of dose adjustment strategies on success rate of Shock Wave Lithotripsy in the clinical setting and to optimize the conditions for successful Shock Wave Lithotripsy. Research Methodology: This clinical trial will be conducted at a tertiary care university hospital. 150 patients referred to the Shock wave lithotripsy unit will be evaluated for eligibility to be randomized into three groups (Dose Escalation, Dose reduction and constant dose). Parameter of the three groups will be compared to detect the treatment difference.

NCT ID: NCT02032316 Completed - Clinical trials for Unilateral Ureteral Stone

Feasibility Study of the Uriprene Stent Following Uncomplicated Ureteroscopy

URIPRENE
Start date: March 2014
Phase: Phase 1
Study type: Interventional

A prospective, single-center, single-arm, trial to demonstrate safety and device performance of the ADVA-Tec Uripreneā„¢ Degradable Temporary Ureteral Stent. This is a first-in-man clinical study in a small human population.

NCT ID: NCT02028559 Active, not recruiting - Urolithiasis Clinical Trials

Safety and Effectiveness of the Ultrasonic Propulsion of Kidney Stones

Start date: January 2014
Phase: N/A
Study type: Interventional

This study tests moving kidney stones using focused ultrasound (referred to as ultrasonic propulsion). The study includes multiple population groups to investigate the ability of our technology to: a) move stone fragments to a location within the kidney to improve their chances of passage, and thus reduce the occurrence of additional symptomatic events and retreatment or b) move a symptomatic stone to relieve symptoms and pain.

NCT ID: NCT02026388 Recruiting - Clinical trials for Primary Hyperoxaluria

Rare Kidney Stone Consortium Biobank

Start date: May 2013
Phase:
Study type: Observational

This study is being done to obtain samples from patients with primary hyperoxaluria, cystinuria, adenine phosphoribosyl transferase (APRT) deficiency, and Dent disease, and from their family members, for use in future research.

NCT ID: NCT02011737 Not yet recruiting - Kidney Calculi Clinical Trials

Naftopidil 75mg for Improving Clearance of Urinary Stones

Start date: February 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate Efficacy and Safety of oral intake of Naftopidil 75mg once daily for the improving clearance of ureteral or renal stones.

NCT ID: NCT02007980 Active, not recruiting - Kidney Calculi Clinical Trials

Indwelling Stent Discoloration Project

Start date: December 2013
Phase:
Study type: Observational

The aim of this study is to identify the root cause for the significant discolouration of Boston Scientific Percuflex based stents.

NCT ID: NCT01990027 Recruiting - Kidney Stone Clinical Trials

Swiss Kidney Stone Cohort (SKSC)

SKSC
Start date: April 2014
Phase: N/A
Study type: Observational [Patient Registry]

The SKSC is a continuous database with the objective of a standardized diagnosis and monitoring of patients with kidney stones as well as the establishment of a Biobank.

NCT ID: NCT01980004 Withdrawn - Kidney Stone Clinical Trials

Potassium Citrate Supplementation vs. Dietary Counseling

Start date: November 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the role of potassium citrate supplementation with dietary education versus dietary education alone in the reduction of stone risks and events in patients with predominantly calcium phosphate kidney stones.

NCT ID: NCT01928108 Completed - Kidney Stone Clinical Trials

Fluid Intake Application to Reduce Kidney Stone Risks

Start date: July 2013
Phase: N/A
Study type: Observational

The purpose of this investigation is to prospectively evaluate the benefit of different methods of educating patients regarding their fluid intake through a readily available daily cellular phone application to improve overall urine output and reduce risk factors for stone recurrence.

NCT ID: NCT01922414 Completed - Kidney Stones Clinical Trials

Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones

Start date: August 2011
Phase: N/A
Study type: Interventional

This study will be conducted to compare the results of Laser and ultrasonic lithotripsy in disintegration of staghorn stones during percutaneous nephrolithotomy.