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Kidney Calculi clinical trials

View clinical trials related to Kidney Calculi.

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NCT ID: NCT06209931 Recruiting - Kidney Stone Clinical Trials

RIRS With Tip Flexible Pressure-controlling Ureteral Access Sheath Versus Mini PCNLfor Kidney Stones

Start date: October 1, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to compare the safety and efficacy between RIRS with tip flexible pressure-controlling ureteral access sheath and mini percutaneous nephrolithotripsy(PCNL) for the treatment of 2-3-cm kidney stones.

NCT ID: NCT06138327 Recruiting - Kidney Stone Clinical Trials

A Study of BMN 255 in Participants With Non-Alcoholic Fatty Liver Disease And Hyperoxaluria

Start date: September 26, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to test the safety of BMN 255 and to learn about the effect BMN 255 has on you and your hyperoxaluria associated with NAFLD, and compare these effects with a placebo. The primary safety objective of the study is to assess the safety and tolerability of daily oral doses of BMN 255 in adult participants with NAFLD and hyperoxaluria. The primary efficacy objective of the study is to assess 24-hour urine oxalate levels (24-hour urine collection corrected for BSA) following daily oral doses of BMN 255 in adult participants with NAFLD and hyperoxaluria.

NCT ID: NCT06085794 Recruiting - Renal Stone Clinical Trials

Standard PCNL Vs Endoscopic Combined Intrarenal Surgery (ECIRS) for Complex Nephrolithiasis in Obese Patients

ECIRS
Start date: July 25, 2022
Phase: N/A
Study type: Interventional

Primary aim: comparing the efficacy of standard PCNL and endoscopic combined intrarenal surgery (ECIRS) in the Galdakao-modified Supine Valdivia (GMSV) position in a single session for the treatment of complex nephrolithiasis in obese patients. Secondary aim: comparing safety and complications of standard PCNL and ECIRS in the GMSV.

NCT ID: NCT06062849 Recruiting - Postoperative Pain Clinical Trials

Is it Really Necessary to Insert a Nephrostomy Tube or Double J Stent in Percutaneous Nephrolithotomy?

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

In this study, investigators aimed to compare the postoperative pain status and comfort situations depending on instruments used in the percutaneous nephrolithotomy operation

NCT ID: NCT06003348 Recruiting - Clinical trials for Calcium Phosphate Kidney Stones

Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

Start date: December 13, 2023
Phase: Phase 4
Study type: Interventional

This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.

NCT ID: NCT05993546 Recruiting - Kidney Stone Clinical Trials

Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis

Start date: August 29, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to compare two variations of the mini-PCNL procedure using either a vacuum-assisted sheath or standard sheath which are both used for the surgical treatment of kidney stones. Both procedure types are commonly used in the treatment of kidneys stones and they have been shown to be safe and effective in the treatment of stones similar in size and location to your own.

NCT ID: NCT05972408 Recruiting - Renal Calculi Clinical Trials

Evaluation of Prevalence, Molecular and Genetic Backgrounds of Calcium-Based Stones Among Patients With Renal Calcular Disease in Mansoura Urology and Nephrology Center

Start date: March 21, 2021
Phase: N/A
Study type: Interventional

Evaluation of Prevalence, Molecular and Genetic Backgrounds of Calcium-Based stones among Patients with Renal Calcular Disease in Mansoura Urology and Nephrology Center

NCT ID: NCT05924165 Recruiting - Nephrolithiasis Clinical Trials

Narcotic-Free Percutaneous Nephrolithotomy

Start date: May 19, 2023
Phase: Phase 4
Study type: Interventional

This is a randomized control trial comparing oral ketorolac and opioid medication for the use of post-operative analgesia.

NCT ID: NCT05872230 Recruiting - Nephrolithiasis Clinical Trials

Massage Percussion for Passage of Urolithiasis Fragments After Ureteroscopy.

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

Flexible ureteroscopy is characterized as first-line therapy for renal stones < 2 cm in size. Stones are commonly treated with dusting or fragmentation techniques which requires passage of stone fragments after surgery. Quoted stone free rate after flexible ureteroscopy is approximately 40-60% with a dusting technique. Residual fragments are often under 1mm in size and can layer in the lower pole of the kidney, complicating spontaneous stone passage. Improving the stone free rate after surgery decreases the need for secondary surgeries and decreases risk of future stone events. Numerous techniques have been proposed to increase stone passage including positional changes and percussion therapy. To date, there is overall limited data a lack of techniques that can be readily available in the outpatient setting, easily added to scheduled appointments, reproducible results and well tolerated by patients.

NCT ID: NCT05869890 Recruiting - Renal Calculi Clinical Trials

Ureteroscopic Laser Modality on Total Lasing Time and Total Energy in Patients With Large, Dense Renal Calculi

Start date: February 22, 2023
Phase: N/A
Study type: Interventional

This study will examine the effects of ureteroscopic lasing technique (dusting, fragmentation and a hybrid approach) on total lasing time and total energy in patients with a large renal calculi burden of single or multiple stones with the sum of its longest diameters between 10-20 mm and having mean Hounsfield units of 1000 or more.