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Clinical Trial Summary

15 healthy trained males will volunteer to participate in this study. there will be 2 treatments: Ketone esters supplementation and iso-caloric carbohydrate. The purpose of this study is to evaluate the effect of ketone esters on cognitive function during exercise after induced mental fatigue


Clinical Trial Description

mental fatigue is often seen in sports of moderate to long duration. its onset is associated with detriments in cognitive function which leads to poor decision making and detriments in specific sport skills. Ketones can serve as a powerful brain fuel source so they may have the potential to delay/ revert the onset of mental fatigue. in this experiment, we will induce mental fatigue in individuals who will be performing 45 minutes of intermittent exercise right after. During exercise cognitive function will be measured under 2 condition, Ketone supplementation and placebo. The purpose of this study is to see if ketones can play a role in reverting that initial mental fatigue during exercise, compared to placebo. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04576026
Study type Interventional
Source Western University, Canada
Contact Peter WR Lemon, PhD
Phone 519 6612111
Email plemon@uwo.ca
Status Not yet recruiting
Phase N/A
Start date October 1, 2020
Completion date October 1, 2021

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