Clinical Trials Logo
  1. Home
  2. Keratoconus
  3. NCT04383366
  4. Details
NCT04383366 Clinical Trial

Agreement and Accuracy of Different Devices Corneal Measurements

Keratoconus Clinical Trial

Official title:
Agreement and Accuracy of Different Devices for the Measurement of Corneal Thickness and Corneal Curvature in Patients With Keratoconus

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04383366
Other study ID # TOPOC
Secondary ID
Status Completed
Phase
First received
Last updated
Start date October 21, 2019
Est. completion date February 6, 2020

Study information
Verified date March 2021
Source Medical University of Vienna
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To compare repeatability, reproducibility and agreement of both, AS- OCT and Scheimpflug imaging, for the measurement of corneal curvature and corneal thickness in patients with keratoconus.

Recruitment information / eligibility
Status Completed
Enrollment 50
Est. completion date February 6, 2020
Est. primary completion date February 6, 2020
Accepts healthy volunteers No
Gender All
Age group 18 Years to 99 Years
Eligibility Inclusion Criteria: - Men and women aged between 18 and 99 years - Presence of keratoconus - Signed informed consent Exclusion Criteria: - Contact lens history within 5 days - Pathologic changes of the lid or conjunctiva on slit-lamp examination - History of corneal ocular surgery/Previous corneal cross-linking

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Pentacam® (Oculus, Inc., Wetzlar, Germany)
Scheimpflug imaging
• Casia II (Tomey Germany, Nürnberg)
Anterior segment optical coherence tomography
• Spectralis Anterion (Heidelberg Engineering, Heidelberg, Germany)
Anterior segment optical coherence tomography

Locations
Country Name City State
Austria Medical University of Vienna, Department of Ophthalmology Vienna

Sponsors (1)
Lead Sponsor Collaborator
Gerald Schmidinger

Country where clinical trial is conducted

Austria, 

Outcome
Type Measure Description Time frame Safety issue
Primary maximum K-value 1 day
Secondary Simulated minimum and maximum K-value 1 day
Secondary Mean K-values 1 day
Secondary Central Corneal thickness 1 day
Secondary Thinnest corneal point 1 day
See also
  Status Clinical Trial Phase
Recruiting NCT04570020 - Scleral Lens Fitting Using Wide-Field OCT
Recruiting NCT02921009 - McNeel Eye Center Corneal Crosslinking Study N/A
Terminated NCT02762253 - Study of the Safety and Effectiveness of Photochemically Induced Collagen Cross-Linking in Eyes With Keratoconus. Phase 2
Completed NCT01691651 - Botulinum Toxin A for the Treatment of Keratoconus N/A
Completed NCT01527708 - Accuracy of Curvature and Wavefront Aberrations of Posterior Corneal Surface, in Keratoconic and Post-CXL Corneas N/A
Completed NCT01527721 - Blurring Strength & Aberrometric Changes Following Corneal Cross-linking (CxL) and CxL Combined With Photorefractive Keratectomy (PRK) in Keratoconus N/A
Recruiting NCT00841386 - Treatment of Keratoconus Using Collagen Cross-Linking Phase 2/Phase 3
Completed NCT00347074 - A Clinical Study of Keratoconus in Asian Patients and Assessment of Different Topographic Patterns of Keratoconus in Asian Patients N/A
Completed NCT03187912 - Accelerated Corneal Cross-linking With Different Riboflavin Solutions Phase 3
Completed NCT00584285 - Corneal Topographer Fluorescein Patterns
Completed NCT03511495 - Reliability of Topography Measurements in Keratoconus
Not yet recruiting NCT05395650 - Cyanocobalamin as Photosensitizing Agent
Completed NCT04418999 - Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Keratoconus Early Phase 1
Completed NCT05019768 - Topo-pachimetric Accelerated Epi-On Cross-linking Compared to Dresden Protocol Using Riboflavin With Vitamin E TPGS N/A
Completed NCT03235856 - Retrospective Digital Computer Analysis of Keratoconus Evolution - REDCAKE
Withdrawn NCT01789333 - Higher Irradiance in Keratoconus Ectasia N/A
Completed NCT05114928 - Correlation Between Q-value Changes and Progression of Pediatric Keratoconus.
Completed NCT03647046 - Custom Anterior Surfacing of Scleral Lens for Vision Quality Improvement in Patients With Keratoconus N/A
Recruiting NCT04439552 - fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Recruiting NCT06100939 - Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus Phase 3