Prevelance of Keratoconus

Keratoconus Clinical Trial

Official title:

Prevelance of Keratoconus in Individuals Attending Refreactive Surgery Centers in Assiut

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04092426
• Other study ID #: keratoconus in assiut
• Status: Not yet recruiting
• Start date: October 1, 2019
• Est. completion date: October 1, 2021

Study information

• Verified date: September 2019
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Keratoconus is a degenerative disease entity characterized by conical shape ectasia of the cornea. progressive conical deformation of the cornea leads to substantial astigmatism. Patients who are at an advanced stage of ectasia are often led to corneal transplant or other treatments, which essentially aim at correcting the refractive error and not in treating the ectasia. The top of the protruding cone that corneal configuration may be close to the visual axis or below and nasal of that. The disease manifests during adolescence, followed by slow progressive course, although it is possible to stabilize anytime. In 85% of cases both eyes are affected, but the severity of the attack can present significant asymmetry.

Description:

Often in keratoconus a positive family history is present. Prevelance of keratoconus varies greatly worldwide.The reported prevalence of keratoconus varies widely depending upon the geographic location, diagnostic criteria used, and the cohort of patients selected. Environmental factors may contribute to the wide variation in prevalence.

the Middle East have higher prevalence than locations with cooler climates and less sunshine

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 300
• Est. completion date: October 1, 2021
• Est. primary completion date: October 1, 2020
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

1. persons attending refractive surgery centers in Asssiut.

2. patients found to have keratoconus are included , based on history , clinical examination and corneal topography

Exclusion criteria :

1. patients not attending those refractive surgery centers.

2. patients attending these centers but not diagnosed to be keratoconus .

3. Pregnancy or breastfeeding

Related Conditions & MeSH terms

• Keratoconus

Intervention

Other:
• opthalmologic examination
opthalmologic examination : Refraction Best corrected visual acuity Intraocular pressure Slit lamp examination

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (1)

Jonas JB, Nangia V, Matin A, Kulkarni M, Bhojwani K. Prevalence and associations of keratoconus in rural maharashtra in central India: the central India eye and medical study. Am J Ophthalmol. 2009 Nov;148(5):760-5. doi: 10.1016/j.ajo.2009.06.024. Epub 2009 Aug 11. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence of keratoconus in different areas in assiut	Number of keratoconus cases detected areas in indivduals attending refractive surgery centers in Assiut	one year