Comparison of Anwar and Melles Techniques in Deep Anterior Lamellar Keratoplasty (DALK) for Keratoconus Patients

Keratoconus Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00850148
• Other study ID #: 8721
• Status: Completed
• Phase: N/A
• First received: February 23, 2009
• Last updated: January 4, 2012
• Start date: May 2008
• Est. completion date: September 2009

Study information

• Verified date: February 2009
• Source: hahid Beheshti University of Medical Sciences
• Contact: n/a
• Is FDA regulated: No
• Health authority: Iran: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

This study will be performed on patients who come to labbafinejad ophthalmic clinic from 20 March 2008. Keratoconus diagnosis will be determined by clinical finding in slit lamp, keratometery and topographic characteristics. Patients will be randomly placed in group A and B. In group A, Anwar surgical method and in B, Melles surgical method, will be done. This is not a blind study due to surgeons' knowledge. All patients will receive Btamethazone drop and Chloramphenicol every 6 hours and will be tapered in two months. In the end anatomical results, complications, BCVA, UCVA, astigmatism, endothelial cell numbers will be compared in two groups by using specular microscopy. Contrast sensivity, central corneal diameter, interface wrinkling and opacity will be measured by metrovison, Confoscan, Photoslit in months 3, 6, 12, respectively and will be evaluated afterwards.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: September 2009
• Est. primary completion date: June 2009
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 15 Years to 45 Years

Eligibility

Inclusion Criteria:

• patients with keratoconus

• 15<age<45

• contact lens intolerance

Exclusion Criteria:

• Having a history of any other ophthalmic or systemic problem

• Central corneal scar

• descemet's membrane detachment

Study Design

N/A

Related Conditions & MeSH terms

• Keratoconus

Intervention

Procedure:
• Anwar
Anwar surgical method
• Melles
Melles surgical method

Locations

Country	Name	City	State
Iran, Islamic Republic of	Farid Karimian,MD	Tehran
Iran, Islamic Republic of	Ophtalmic Research Centre	Tehran

Sponsors (1)

Lead Sponsor	Collaborator
hahid Beheshti University of Medical Sciences

Country where clinical trial is conducted

Iran, Islamic Republic of,