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Keratoconus clinical trials

View clinical trials related to Keratoconus.

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NCT ID: NCT06119321 Active, not recruiting - Clinical trials for Scansys, Pentacam, Corvis ST, Keratoconus, Subclinical Keratoconus

A Study of a Novel Scheimpflug Device in Diagnosing Keratoconus

Start date: May 4, 2023
Phase:
Study type: Observational

Comparison of the screening and diagnosis ability of the novel Scheimpflug-based tomography device (Scansys) with Pentacam and the Scheimpflug-based biomechanics device (Corvis ST) for keratoconus.

NCT ID: NCT05596838 Active, not recruiting - Keratoconus Clinical Trials

Long-term Result of Placing Intracorneal Rings in Keratoconus Using Laser

STAK
Start date: January 20, 2023
Phase:
Study type: Observational

Intracorneal rings are indicated in patients whose central cornea does not present opacity and whose visual acuity is not satisfied despite correction with lenses or linked to an intolerance to lenses. Surgeries such as crosslinking and intracorneal rings placement are alternatives to corneal transplantation with the expected effects: stabilization of the disease for corneal collagen crosslinking and visual rehabilitation by the placement of intracorneal rings. The main objective of this study is to evaluate visual benefit1 year after placement of intracorneal rings using laser in keratoconus

NCT ID: NCT05220904 Active, not recruiting - Keratoconus, Stable Clinical Trials

Perceptual Learning Improve Visual Function in Patients With Keratoconus

KPL
Start date: February 5, 2022
Phase: N/A
Study type: Interventional

This project aims at non-progressive keratoconus patients with unsatisfactory visual acuity corrected by spectacles, and explores the effectiveness and maintenance of visual acuity improved by perceptual learning.

NCT ID: NCT05176171 Active, not recruiting - Keratoconus Clinical Trials

Surface Ablation With Corneal Cross Linking in Mild Keratoconus

Start date: March 5, 2018
Phase: N/A
Study type: Interventional

Interventional and comparative prospective study: Sixty-nine eyes (38 patients) suffering from keratoconus (stages 1-2 Amsler-Krumeich classification) will be divided into four groups. The four groups underwent topography- and non-topography-guided PRK with sequential and simultaneous CXL. The main outcome measures will be pre-and postoperative uncorrected distance visual acuity (UDVA), best-corrected distance visual acuity (CDVA), manifest refraction, contrast sensitivity, and keratometry

NCT ID: NCT04895514 Active, not recruiting - Keratoconus Clinical Trials

Gamma-Irradiated Corneal Inlay for Keratoconus

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Study objective is to evaluate the outcomes of placing gamma-irradiated corneal tissue (VisionGraft, CorneaGen, USA) within the cornea of patients with keratoconus, a procedure called Corneal Tissue Addition for Keratoconus (CTAK).

NCT ID: NCT04820608 Active, not recruiting - Keratoconus Clinical Trials

Transepithelial Customized Cross-linking

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Customized remodeled vision (CuRV) is a new corneal cross-linking protocol for keratoconus, combining a transepithelial approach with customized energy application. Our aim is to follow-up our patients and establish the short-and long-term results of CuRV.

NCT ID: NCT04763785 Active, not recruiting - Cataract Clinical Trials

Development of a Keratoconus Detection Algorithm by Deep Learning Analysis and Its Validation on Eyestar Images

DKDA
Start date: May 11, 2021
Phase:
Study type: Observational

Monocentric clinical study to develop an imaging analysis algorithm for the Eyestar 900 to identify keratoconus corneas and improve biometry for intraocular lens calculations

NCT ID: NCT04698590 Active, not recruiting - Keratoconus Clinical Trials

Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism

WFG Sclerals
Start date: January 15, 2021
Phase: N/A
Study type: Interventional

Aberrations are the spreading of light from a point focus. Aberrations of the eyes can be objectively evaluated with a wavefront aberrometer. Lower order aberrations such as defocus and astigmatism can be corrected with glasses and traditional/disposable soft contact lenses. Patients with ectatic corneal disease, such as keratoconus, or irregular astigmatism cause by surgery, trauma or disease, experience vision that is unlikely to be adequately corrected with glasses or disposable soft contact lenses due to higher order aberrations (HOA). HOA's cause halos, flare, glare, starbursts, doubling, smearing or ghosting of vision. Specialty contact lenses, such as scleral lenses, can be used to mask the irregularity of the cornea, reducing HOA's and improving vision. In many patients the resultant vision, though improved, still has some level of residual HOA's affecting the quality of vision. Custom scleral lenses with customized wavefront guided optics can be used to reduce residual HOA's and improve vision further. These lenses have been referred to as higher order aberration correcting scleral lenses or HOA correcting sclerals and wavefront guided scleral lenses or WFG sclerals.

NCT ID: NCT04668924 Active, not recruiting - Keratoconus Clinical Trials

Epi-on PiXL for the Treatment of Progressive Keratoconus.

Start date: March 20, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety and postoperative ocular discomfort by individually customized Photorefractive intrastromal crosslinking (PiXL) without epithelium debridement in high oxygen environment (Epi-on) for progressive Keratoconus.

NCT ID: NCT04667572 Active, not recruiting - Keratoconus Clinical Trials

Safety & Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution

Start date: February 1, 2021
Phase: Phase 1
Study type: Interventional

Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Collagen Cross-linking in Eyes With Corneal Thinning Conditions