Keloid Clinical Trial
Official title:
Efficay of Autologous Platelet Rich Plasma Obtained With RgenKit-BCT in the Prevention and the Treatment of Keloid Scars
The aim of this prospective study is to assess the efficacy of autologous Platelet Rich Plasma prepared with RegenKit-BCT in the prevention and the treatment of keloid scars refractory to conventional treatments. Fifteen patients were included and received three PRP injection sessions with a one-month interval. The outcomes were assessed at baseline (before treatment), 3, 6, 12 and 24 months after the last injection session. Safety was assessed by reported adverse event analysis.
To evaluate the efficacy and the safety of platelet rich plasma in the treatment of keloid scars. This prospective, comparative study (before-after treatment) included 15 patients with keloid scars refractory to conventional treatment (corticoids, surgery, cryotherapy). The primary outcome was the percentage of patients achieving a complete remission of their keloid scar 2 years after the end of treatment. Secondary outcomes were the Vancouver scar scale and pruritus severity scored at 3, 6, 12 and 24 months post treatment vs baseline. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT02923596 -
Retrospective Study of Keloid Disorder
|
N/A | |
| Terminated |
NCT01478243 -
Study of Psycho-Social Impact of Keloid
|
N/A | |
| Recruiting |
NCT01423383 -
Epidemiology Study of Keloid
|
N/A | |
| Completed |
NCT03228693 -
Gene Expression and Biomarker Profiling of Keloid Skin
|
N/A | |
| Not yet recruiting |
NCT04326959 -
Implantation of Mesenchymal Stem Cell, Conditioned Medium, or Triamcinolone Acetonide for Keloid
|
Phase 1/Phase 2 | |
| Recruiting |
NCT03312166 -
Compressive Device to Prevent Keloïd Scars Recurrence [SCARWARS]
|
N/A | |
| Recruiting |
NCT02823236 -
Efficacy of Intralesional Triamcinolone and 8% Topical Pirfenidone for Treatment of Keloid Scars
|
Phase 3 | |
| Recruiting |
NCT04597060 -
The Safety and Efficacy of Thermo-mechanical System for Fractional Ablation Associated Triamcinolone Acetonide Drug Delivery for the Treatment of Hypertrophic Scars and Keloids
|
N/A | |
| Completed |
NCT05887804 -
Comparison of Keloid Volume and Symptoms Reduction Between Intralesional Umbilical-Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide Injection as Keloid Therapy: A Randomised Controlled Trial
|
Phase 4 | |
| Completed |
NCT05939817 -
The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide on Type 1:3 Collagen Ratio and Interleukin-10 Levels in Keloid: A Randomised Controlled Trial
|
Phase 4 | |
| Completed |
NCT03630198 -
Pain Outcomes Following Intralesional Corticosteroid Injections
|
Phase 4 | |
| Completed |
NCT04169438 -
Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions
|
N/A | |
| Recruiting |
NCT01423981 -
Web Based Investigation of Natural History of Keloid Disorder, an Online Survey
|
N/A | |
| Completed |
NCT01446770 -
Evaluation of the Initial Safety and Efficacy of Keloid Lesions Treated With MF-4181
|
Phase 2 | |
| Recruiting |
NCT06138964 -
Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars
|
Phase 3 | |
| Enrolling by invitation |
NCT05461157 -
Preoperative Silicone Ointment and Wound Healing
|
N/A | |
| Not yet recruiting |
NCT04593706 -
Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars)
|
N/A | |
| Enrolling by invitation |
NCT04988022 -
Dupilumab in the Treatment of Keloids
|
Phase 4 | |
| Withdrawn |
NCT02546076 -
Comparison of Dual-mode ER:YAG Laser in Patients With Long Keloid/Hypertrophic Scars
|
Phase 2 | |
| Completed |
NCT02340325 -
FS2 Safety and Tolerability Study in Healthy Volunteers
|
Phase 1 |