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Clinical Trial Summary

This study aims to examine both the genetic profile and the biomarkers implicated in keloid scar formation. Hypothesis: 1. Differences in the genetic profiles of lesional and non-lesional skin contribute a given population's propensity to develop keloids 2. Differences in biomolecules expressed in subjects with and without keloids can help predict keloid occurrence and severity 3. Biomarker analysis will provide useful insights for future targeted therapies for keloid scars


Clinical Trial Description

Objectives: 1. Determine gene expression profiles of keloid scar tissue using samples collected longitudinally 2. Define and compare the molecular biomarkers of keloid scars in keloid (lesional) and non-lesional skin biopsies and serum samples from adult subjects ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03228693
Study type Interventional
Source Northwestern University
Contact
Status Completed
Phase N/A
Start date September 11, 2017
Completion date January 31, 2023

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