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Joint Diseases clinical trials

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NCT ID: NCT06053008 Recruiting - Pain Clinical Trials

The Relationship Between Pain Perception, Severity of Temporomandibular Joint Dysfunction, and Spinal Health in Geriatric Individuals

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

It is aimed to examine the relationship between pain perception, temporomandibular joint disorder severity and spine health in elderly individuals.

NCT ID: NCT06052735 Recruiting - Pain Clinical Trials

Association Among Pain Perception, Severity of Temporomandibular Joint Dysfunction, and Spinal Health in Caregivers of Stroke Individuals

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

This study aims to examine pain perception, temporomandibular disorder severity and spine health in caregivers of stroke patients.

NCT ID: NCT06046521 Recruiting - Clinical trials for Temporomandibular Joint Disorders

Impact of Temporomandibular Joint Dysfunction on Objective and Subjective Vocal Measures

Start date: September 20, 2023
Phase:
Study type: Observational

The present study aims to investigate the impact of temporomandibular joint dysfunction (TMD) on objective and subjective vocal parameters and the quality of life in affected patients. TMD is a pervasive public health issue that impacts approximately 25% of the general population and is notably more prevalent among women. The etiology of TMD is multi-factorial, with known risk factors such as parafunctional habits, emotional stress, occlusion issues, and orthodontic treatments. Internal derangements of the temporomandibular joint are the most common subtype of TMD, characterized by symptoms such as pain, joint noises, restricted mouth opening, and masticatory dysfunction. This study particularly focuses on the limitations in mouth opening due to TMD and its effects on vocal characteristics and quality of life. Conservative treatment methods, such as non-steroidal anti-inflammatory drugs (NSAIDs) and occlusal splints, have been effective in symptom management unless there is clear evidence of joint collapse or ankylosis. The null hypothesis (H0) posits that the restriction in mouth opening has no impact on vocal parameters or quality of life.

NCT ID: NCT06045182 Recruiting - Sacroiliac Joint Clinical Trials

Additional Effects of Piriformis Stretch in the Management of Sacroiliac Joint Dysfunction

Start date: August 30, 2023
Phase: N/A
Study type: Interventional

Sacroiliac joint (SIJ) dysfunction is known as an important contributing factor in lower back pain. Pain and stiffness experienced from the sacroiliac joint in the SI region (hips/groins or may spread to lower extremity) is referred as SIJ dysfunction.Physiotherapists have a wide range of options in managing SIJD including Manipulation, Kinesiotaping, Muscle Energy Technique (MET), McKenzie, Maitland's mobilization, and Mulligan's mobilization. So far studies have shown the efficacy of different treatment tools in combination or in isolation. Likewise, researchers have also studied the effect of piriformis stretch in combination with other exercises on sacroiliac joint pain. However, there is very limited literature available on the cumulative effect of piriformis stretch along with mobilization maneuvers on pain and disability in patient with SIJ dysfunction.Since piriformis is one of the most important muscles involved in stabilization of SI joint and a major source of SI dysfunction, hence the current study is designed to investigate the additional effects of piriformis stretch with manual therapy in the management of sacroiliac joint dysfunction.

NCT ID: NCT06043024 Recruiting - Clinical trials for Temporomandibular Joint Disorders

Characteristics of Cytokine Response in Patients With Temporomandibular Disorders Treated With Occlusal Splint Therapy

Start date: August 16, 2023
Phase: N/A
Study type: Interventional

The goal of this intervention study is to determine the effect of occlusal splint (OS) therapy on the concentration of inflammatory cytokines in serum and gingival crevicular fluid (GCF) in patients with temporomandibular disorders (TMDs). Aims are: - to determine cytokines level in GCF and serum before and after OS therapy - to determine the degree of psychosocial dysfunction and oral health-related quality of life before and after OS therapy - investigate the correlation between cytokines level in GCF and serum - to determine the effect of OS on treatment outcomes, pain intensity, dysfunction, and psychosocial status of patients with painful TMD. Participants will be asked to complete self-assessment questionnaires, and GCF and blood samples will be collected before beginning of the OS therapy and at follow-up examinations one month and two months after.

NCT ID: NCT06035341 Recruiting - Clinical trials for Temporomandibular Disorder

The Association Between Temporomandibular Disorders and Sacroiliac Joint Dysfunction

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the relationship between Temporomandibular Disorders (TMD) and Sacroiliac Joint Disfunction (SIJD) and to determine the immediate effect of single-session orofacial manual therapy on SIJD. Patients will be treated for 1 session. The evaluation was planned to be done twice, at the beginning and end of the session.

NCT ID: NCT06005623 Recruiting - Knee Arthropathy Clinical Trials

Motivational Feedback Following Total or Unicompartmental Knee Arthroplasty

KneeActivity
Start date: September 15, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized controlled trial (RCT) nested in a prospective cohort study is to investigate whether physical activity (PA) following total knee arthroplasty (TKA) or unicompartmental knee arthroplasty (UKA) can be optimized by the use of an activity tracking device including motivational feedback in comparison with activity tracking without feedback. Furthermore, the project will investigate the predictive value of PA level prior to TKA/UKA for the length of stay, return to work, and quality of life. The main hypothese of the study are: RCT study: - Using an activity tracking device, including motivational feed-back on PA show a superior short-term effect on increased PA (Total counts; primary outcome measure), physical functioning, return to work, and quality of life in comparison with no motivational feed-back from the activity tracker, defined as 'care as usual', in TKA and UKA patients - Using an activity tracking device, including motivational feedback, will have a superior effect on step counts, activity types and pain compared to the standard care, in TKA and UKA patients Prospective cohort: - PA prior to TKA or UKA can work as a predictive measure for function and quality of life following surgery - PA prior to TKA or UKA can work as a predictive measure for the length of hospital stay and return to work Patients will be randomized to activity tracking and motivational feed-back by gamification for patient self-mobilization (Intervention-group) or 'care-as-usual' including activity tracking without motivational feed-back (Control-group). Patients not eligible and/or willing to participate in the RCT study, will be offered to participate in a prospective non-interventional cohort study.

NCT ID: NCT06001853 Recruiting - Clinical trials for Facet-Mediated Low Back Pain

Allogeneic BM-MSC's in Patients With Lumbar Facet Arthropathy

Start date: November 3, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this research study is to evaluate the safety and effect of bone marrow-derived stem cells for the treatment of low back pain.

NCT ID: NCT05989217 Recruiting - Clinical trials for Temporomandibular Joint Disorders

Conservative Therapies in the Treatment of Temporomandibular Disorders

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The present study was designed to compare the effects of the mixed occlusal device using the simplified technique and the low-intensity laser alone or in combination in patients with temporomandibular disorders. A total of 96 patients will be selected after the diagnosis of TMD according to the Diagnostic Criteria for Temporomandibular Disorder (DC/TMD), axis I. Patients will be randomly divided into three groups: Occlusal Device (N=32), Laser (N=32) =32) and Occlusal Device and Laser (N=32). Patients undergoing therapy with a stabilizing plate made using the simplified technique will be instructed to use the device every night while sleeping for four weeks. Photobiomodulation will be applied with low-intensity laser at predetermined points and at specific trigger points identified during the clinical examination (3 J/cm2) once a week for four weeks. The intensity of pain will be classified using the Visual Analog Scale (VAS). Mandible function will be assessed by maximum unassisted mouth opening. The impact of therapies on oral health will also be evaluated through the Oral Health Impact Profile (OHIP-14) instrument in a simplified form. The ANOVA test will be used to compare the results obtained between the study groups, while the Repeated Measurements Anova test complemented by the Tukey test will be used for longitudinal evaluation of the data within each group.

NCT ID: NCT05967637 Recruiting - Arthropathy of Knee Clinical Trials

The Effect of Whole-Body Vibration Treatment Before Total Knee Arthroplasty

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The study's objective is to investigate the effects of whole-body vibration therapy administered before surgery on various factors related to patients who undergo total knee arthroplasty. These factors include pain, swelling, skin temperature, normal joint movement, knee joint position sense, knee extensor muscle strength, functional status, and patient satisfaction.