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Joint Diseases clinical trials

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NCT ID: NCT05638386 Completed - Clinical trials for Complication of Surgical Procedure

Effect of Plugging the Registration Pin Tract in Robotic-assisted Knee Surgery

Start date: December 1, 2022
Phase:
Study type: Observational

Introduction: Complications of robotic-assisted total knee arthroplasty (TKA) seem to be rare and consist mainly of infections or fractures. In the Reinier Haga Orthopedisch Centrum (RHOC), postoperative bleeding is experienced to be a complication that often occurs, mainly at the tibial wounds of the registration pins used in robotic-assisted TKA. This often results in longer hospital stay and might interfere with the current fast track knee surgery by a delayed discharge. To overcome this complication, nowadays bone plugs are used in the two drill-holes. Currently, it is unknown whether these bone plugs reduces the incidence of postoperative bleeding. Objective: To evaluate the incidence of postoperative bleeding in patients that underwent a robotic-assisted TKA and received bone plugs in the two drill-holes in the tibia, compared to patients that underwent the same operation but did not receive bone plugs. Study design: Retrospective, inventory study Study population: All patients that underwent a robotic-assisted TKA in the RHOC from December 2020 till October 2022. Intervention: In the past, some patients that underwent a robotic-assisted TKA received a bone plug in the two tibial drill-holes. This bone is collected from the excess bone that is removed during the operation. Main study parameters/endpoints: Incidence of postoperative bleeding in both groups.

NCT ID: NCT05637372 Completed - Clinical trials for Temporomandibular Joint Disorders

Relationships Between Anterior and Condylar Guidance - Comparison by CBCT and Electronic Axiography

Start date: July 20, 2022
Phase:
Study type: Observational

The aim of the following study was to investigate the existence of a statistically significant correlation between the incisal features (incisal guidance angle, interincisal angle, overbite, overjet), temporomandibular joint (TMJ) morphology and its function. The hypothesis was: I. The protrusive movement of the mandible does correlate with the TMJ anatomy. II. The protrusive movement of the mandible does not correlate with the incisal features. III. The position and relationship of upper and lower permanent incisors do not have a direct and significant effect on the TMJ morphology in young adults.

NCT ID: NCT05619380 Recruiting - Pain Clinical Trials

Effectiveness of Physiotherapy Treatments in Temporomandibular Joint Dysfunction

Start date: November 20, 2022
Phase: N/A
Study type: Interventional

The study will determinate the influence of four selected physiotherapeutic procedures on the pain intensity, the bioelectrical activity of the masseter muscle, and the range of mandibular mobility in patients with TMDs (temporomandibular joint dysfunction).

NCT ID: NCT05618782 Active, not recruiting - Pain Clinical Trials

Clinical Trial to Evaluate the Efficacy and Safety of LEVI-04 in Patients With Osteoarthritis of the Knee

Start date: October 17, 2022
Phase: Phase 2
Study type: Interventional

This is a phase 2, randomized, double-blind, placebo-controlled trial of multiple doses and multiple administrations of LEVI-04 for the treatment of pain due to osteoarthritis of the knee.

NCT ID: NCT05602753 Recruiting - Smoking Cessation Clinical Trials

Smoking Cessation Study

Start date: February 18, 2021
Phase:
Study type: Observational

The primary outcome of this study is to determine the true incidence of smokers among patients undergoing joint replacement and secondly, what percent are able to quit smoking before surgery under a structured cessation program with carbon monoxide breath testing. The investigators hypothesize that self-reported smoking status is underreported and that routine carbon monoxide breath testing will improve abstinence rates at the time of surgery.

NCT ID: NCT05594511 Recruiting - Clinical trials for Temporomandibular Joint Disorders

Mandibular Muscle Energy Technique in Patients With Mandibular Joint Pathology and Bruxism

Start date: April 25, 2022
Phase: N/A
Study type: Interventional

This is a randomized, controlled, double-blind clinical trial. The main objective is to evaluate the immediate effect of the mandibular muscle-energy technique on pain, functionality and kinesiophobia in subjects suffering from temporomandibular dysfunction and bruxism. In the experimental group the jaw muscle-energy technique will be applied and in the control group a placebo technique will be applied. The intention is to see the immediate effects of the intervention and two evaluations of the pre- and post-intervention outcome variables and a follow-up of kinesiophobia one week later will be performed.

NCT ID: NCT05591859 Recruiting - Hip Osteoarthritis Clinical Trials

Restoration Anatomic Acetabular Shell Revision Study

RAS
Start date: March 2, 2024
Phase: N/A
Study type: Interventional

This study will be a non-randomized, ambidirectional (retrospective and prospective) study where all subjects will be followed prospectively. The study will evaluate the survivorship of the RAS acetabular component in a previously failed total hip arthroplasty (THA) in a consecutive series of subjects who meet the eligibility criteria.

NCT ID: NCT05589662 Not yet recruiting - Clinical trials for Hemophilia Arthropathy

Clinical, Functional and Musculoskeletal Differences Between Adult Patients With Hemophilia and Their Healthy Peers

Start date: November 21, 2022
Phase:
Study type: Observational

Background. Hemophilia is characterized by the development of a progressive, degenerative, intra-articular lesion (hemophilic arthropathy). This arthropathy presents with chronic pain, limited range of motion, axial changes, and periarticular muscle atrophy. Goal. To analyze the clonic, functional and musculoskeletal differences between adult patients with hemophilic arthropathy of the knee and ankle and their healthy peers. Study design. Cases and controls study patients. 21 patients with hemophilia A and B and 21 subjects without joint damage. Variables and measuring instruments: pressure pain threshold (pressure algometer); joint status (Hemophilia Joint Health Score scale); and strength (dynamometry) and muscle activation (surface electromyography). Expected results. Observe the differences between patients with knee and ankle arthropathy and their healthy peers in muscle strength and activation.

NCT ID: NCT05583630 Recruiting - Knee Arthropathy Clinical Trials

Ligament Tension Measurement in Knee Arthroplasty

Start date: October 20, 2022
Phase:
Study type: Observational

1. To develop a new type of knee joint pressure detection device and demonstrate its feasibility 2. To analyze individual differences of knee ligament tension using the new device and explore the influencing factors of ligament tension 3. To explore the correlation between knee ligament tension and postoperative knee function

NCT ID: NCT05575700 Recruiting - Postoperative Pain Clinical Trials

Safety of Ibuprofen After Major Orthopaedic Surgeries

PERISAFE
Start date: April 17, 2023
Phase: Phase 4
Study type: Interventional

Safety of an eight-day treatment with ibuprofen after primary hip and knee arthroplasties.