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Joint Diseases clinical trials

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NCT ID: NCT05702593 Recruiting - Clinical trials for Temporomandibular Joint Disorders

Immediate Effects of Hamstring Stretching Alone or Combined With Myofascial Release

Start date: July 22, 2022
Phase: N/A
Study type: Interventional

To assess the immediate effects of hamstring stretching alone or combined with myofascial release of the hamstring muscle on masseter muscle activity, pressure pain threshold, active mouth opening, hamstring flexibility, and forward head flexed posture in recreationally active participants. The young, healthy, recreationally active adults aged 18-25 years were included in the study. The participants were randomly separated into two groups of equal number. Static stretching alone was applied to one group and this was combined with myofascial release techniques (SSMR) for the other group. Masseter muscle activity was assessed using a NORAXON® surface electromyography device. Both pre-and post-intervention, mechanical pressure algometer was used to measure the pressure pain threshold, hamstring flexibility was evaluated using the maximum hip flexion and active knee extension test, the maximum mouth opening (MMO) was measured with the millimetric ruler, and forward flexed posture was evaluated using the tragus to wall distance test.

NCT ID: NCT05696418 Completed - Clinical trials for Arthroplasty Complications

Anterior Knee Pain in Mobile Bearing Versus Fixed Bearing in TKA

Start date: January 15, 2021
Phase: N/A
Study type: Interventional

Osteoarthritis is the most common cause of chronic joint disease, and its incidence has increased due to the high average life expectancy, in addition to the high incidence of obesity. Total knee arthroplasty is currently an accepted treatment for severe degenerative conditions and there are various implant systems with special features depending on component geometry, degree of fit of the articular surfaces, and fixation techniques. A tibial component with mobile polyethylene has been developed as an alternative to fixed polyethylene because it has theoretical advantages in terms of increasing the range of motion, reducing wear conditions, and reducing the incidence of anterior knee pain when the articular surface of the patella is not resurfaced.

NCT ID: NCT05693311 Not yet recruiting - IBD Clinical Trials

Inflammatory Bowel Disease Related Joint Manifestations

Start date: March 1, 2023
Phase:
Study type: Observational

The main purpose of this research is to identify incidence of jiunt manifestations by its both types axial and periphral in IBD patients, its types , relation to IBD activity, lines of treatment using and how they are effective in prevention and in treatment of these joint manifestations.

NCT ID: NCT05690347 Recruiting - Arthropathy of Knee Clinical Trials

Protocol for a Multicenter Study on (Cost)Effectiveness of the Back At Work After Surgery (BAAS): a Clinical Pathway for Knee Arthroplasty

Start date: January 1, 2022
Phase:
Study type: Observational

Background Optimizing return to work (RTW) after knee arthroplasty (KA) is becoming increasingly important due to a growing incidence of KA and poor RTW outcomes after KA. We developed the Back At work After Surgery (BAAS) clinical pathway for optimized RTW after KA. Since the effectiveness and cost analysis of the BAAS clinical pathway are still unknown, analysis on effectiveness and costs of BAAS is imperative. Method This protocol paper has been written in line with the standards of Standard Protocol Items: Recommendations for Interventional Trails. To assess the effectiveness and cost-effectiveness for RTW, we will perform a multicenter prospective cohort study with patients who decided to receive a total KA (TKA) or an unicompartmental KA (UKA). To evaluate the effectiveness of BAAS regarding RTW, a comparison to usual care will be made using individual patient data on RTW from prospectively performed cohort studies in the Netherlands. Discussion One of the strengths of this study is that the feasibility for the BAAS clinical pathway was tested at first hand. Also, we will use validated questionnaires and functional tests to assess the patient's recovery using robust outcomes. Moreover, the intervention was performed in two hospitals serving the targeted patient group and to reduce selection bias and improve generalizability. The limitations of this study protocol are that the lead author has an active role as a medical case manager (MCM) in one of the hospitals. Additionally, we will use the data from other prospective Dutch cohort studies to compare our findings regarding RTW to usual care. Since we will not perform an RCT, we will use propensity analysis to reduce the bias due to possible differences between these cohorts.

NCT ID: NCT05673642 Recruiting - Low Back Pain Clinical Trials

Effect of Myofascial Release Technique Applied to in Patients With Temporomandibular Dysfunction

Start date: May 10, 2021
Phase: N/A
Study type: Interventional

We aim to compare the effectiveness of MFR and exercise therapy on mobility and function by investigating the effectiveness of the Myofascial Release Technique (MFR), which we will apply to the muscles we choose related to the facial system connection in participants with temporomandibular dysfunction (TMD) and low back pain.

NCT ID: NCT05671549 Completed - Clinical trials for Temporomandibular Joint Disorders

Combined Arthrocentesis and Occlusal Splint Therapy for Closed Locks of the TMJ

Start date: May 29, 2019
Phase: N/A
Study type: Interventional

The goal of this prospective cohort study is to evaluate the effectiveness of combined arthrocentesis and occlusal stabilization splint therapy in patients diagnosed with disc displacement without reduction of temporomandibular joint-induced closed locks. The main questions it aims to answer are: - Is there a difference in the treatment response between chronic and acute closed-lock conditions? - On which dimensions of pain did the treatment have positive effects? Participants will be preoperatively examined and assigned to one of the two study groups. - All participants undergo a single session of TMJ arthrocentesis. - Following the arthrocentesis session, all participants will use preoperatively fabricated occlusal splints. - Participants will be recalled in one week to evaluate the outcomes. Researchers will compare acute and chronic closed-lock groups to see if there are differences between pain intensities and mouth-opening amounts postoperatively.

NCT ID: NCT05657847 Recruiting - Clinical trials for Arthritis, Rheumatoid

Novel Complex Radiodiagnostics of Peripherial Arthropathies

Start date: March 7, 2022
Phase:
Study type: Observational

Chronic peripherial arthritides are common diseases with soaring public health consequences. Our goal is to assess the role of photon-counting detector computed tomography in the diagnostics of peripherial arthropathies.

NCT ID: NCT05651256 Completed - Clinical trials for Temporomandibular Joint Disorder Bilateral

Efficacy of Botulinum Toxin in Temporomandibular Disorders

TMD
Start date: March 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Temporomandibular disorders (TMDs) represent a multifactorial pathological group that gives rise to a varied and complex symptomatology that includes decreased jaw movement, muscle and joint pain, joint crepitation and limitation or functional deviation of the jaw opening. All this is sometimes accompanied by headache and other painful symptoms in the neck musculature, incapacitating for many patients and at considerable public health expense. Intramuscular and intra-articular injections of botulinum toxin are a simple treatment that has proven to be effective in the treatment of the painful symptoms of these disorders, being a therapeutic option in situations of failure of conventional treatments, without presenting adverse effects. Our study presents the preliminary results of twenty patients treated with this therapy

NCT ID: NCT05650970 Completed - Joint Diseases Clinical Trials

Radial Nerve Mobilization in Hand Thumb Osteoarthritis Patients

Start date: November 5, 2022
Phase: N/A
Study type: Interventional

Hand-thumb carpometacarpal (1st CMC) joint osteoarthritis is defined as the degeneration occurring between the articular surfaces of the 1st metacarpal bone and the trapezium bone. This degeneration causes deterioration in the cartilage tissue that forms the joint structure, and as a result, patients primarily complain of pain and related loss of function. Clinical observations and studies have shown that the level of pain expressed by patients is not always compatible with the amount of degeneration in the joint. In addition, it has been clearly stated in the studies that the pain complaints of the patients are not only due to the changes in the joint, but the irritation of the nerves that receive the sensation of this joint is also effective in the level of pain. In line with the findings of the studies on this subject, mobilization exercise for the relevant nerve is included in the treatment programs of patients diagnosed with 1st CMC joint osteoarthritis in the clinic for a while. The investigators observed that the radial nerve mobilization exercise given during the process contributed to the improvement in the pain level of the patients. The investigators planned our study because there was no publication in the literature examining this effect. This study aims to investigate the effect of radial nerve mobilization exercise on pain level, functional status, and grip strength of patients diagnosed with 1st CMC joint osteoarthritis.

NCT ID: NCT05649007 Recruiting - Arthropathy of Hip Clinical Trials

Post-marketing Surveillance Study of the Saphir Stem in Primary Hip Surgery

Start date: September 30, 2022
Phase:
Study type: Observational

Post-market clinical follow up investigation on the use of saphir stem and FIN Cup or Dualis system in the treatment of pathologies requiring hip arthroplasty. The main object of the clinical investigation is the evaluation of long term survival rate of Saphir stem.