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IVF clinical trials

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NCT ID: NCT04130139 Active, not recruiting - Education Clinical Trials

Benefits of an Oocyte Pickup Simulation Training Program

Start date: August 1, 2017
Phase:
Study type: Observational

The primary objective of this study was to evaluate oocyte pick up simulation training program for teaching residents. The secondary objectives were to evaluate resident satisfaction and the overall current state of oocyte pick up training in France.

NCT ID: NCT04108039 Completed - Infertility Clinical Trials

Micronized Progesterone vs Gonadotropin-releasing Hormone (GnRH) Antagonist in Freeze-all IVF Cycles.

Prog_STIM
Start date: September 25, 2019
Phase: N/A
Study type: Interventional

To examine whether the number of euploid embryos following ovarian stimulation with micronized progesterone is equivalent as compared with the number of embryos after ovarian stimulation with the use of a GnRH antagonist in patients undergoing ovarian stimulation for IVF or intracytoplasmatic sperm injection (ICSI).

NCT ID: NCT04099784 Completed - Infertility Clinical Trials

Health of Frozen Transferred Versus Fresh Transferred Children

Start date: September 1, 2019
Phase:
Study type: Observational

In order to give strong recommendation on the efficacy and safety of fresh versus frozen embryo transfer, we conduct this study in order to investigate the physical and mental development of children from fresh versus frozen embryo transfer. Based on our Freeze-only study (Vuong et al., 2018), the women without polycystic ovary syndrome undergoing the first or second IVF were randomly assigned to receive either fresh or frozen embryos on day 3 after oocyte retrieval, which leads to the similarity in characteristics of these two groups. Hence, the result from analysing these offsprings would be preciously valuable.

NCT ID: NCT04052464 Completed - Infertility, Female Clinical Trials

The Study of the Implantation Window From Endometrial Biopsy With Gene Expression Methods

Start date: September 26, 2016
Phase:
Study type: Observational

The objective of the study is to gain a better understanding of the gene expression changes in the endometrial biopsy especially whether the endometrium has reached a receptive status, i.e. the implantation window, or not.

NCT ID: NCT04048772 Active, not recruiting - Quality of Life Clinical Trials

CALM IVF (Creating Affiliations, Learning, and Mindfulness for In Vitro Fertilization Patients)

Start date: August 9, 2019
Phase: N/A
Study type: Interventional

The investigators have designed a psychoeducational group curriculum specifically for new in vitro fertilization (IVF) patients (both male and female) to improve their treatment knowledge, to allow them to engage more in their care, to offer a support network, to improve satisfaction, and to provide them with tools to help reduce their stress and anxiety while undergoing the IVF process. The investigators plan to have four to eight infertility patients and their partners participate in a group at a time, for which they will attend three 1-1.5 hour interactive sessions that are scheduled throughout their first IVF cycle. These sessions will provide additional time for discussion about treatment with providers, learning opportunities on topics of interest to fertility patients, and stress reduction techniques. They will do several surveys before and after the intervention for comparison, including assessment of quality of life, depression, anxiety, resilience, and a knowledge assessment. The investigators will also track the patients to see if they pursue additional treatment in the instance of a negative pregnancy test compared to patients undergoing the standard treatment. The investigators plan to recruit a control group that receives the standard of care treatment here at the University of Iowa.

NCT ID: NCT04048486 Completed - IVF Clinical Trials

Children Born From IVM-CAPA vs IVF or Natural Conception

Start date: August 7, 2019
Phase:
Study type: Observational

CAPA-IVM is a new promising IVM technique involving the use of a new compound to facilitate the oocyte and embryo competence. CAPA-IVM preserved the maintenance of trans-zonal projections and significantly improved maturation rate and blastocyst yield. NGS analysis of 20 good quality CAPA-IVM blastocysts did not reveal increased aneuploidy compared to age-matched routine ICSI patients. The first CAPA-IVM baby was born in 2017 at My Duc Hospital, Vietnam and up to now, there are 33 babies born from this technique. There is no study to investigate the development of babies born from CAPA-IVM.

NCT ID: NCT04044599 Recruiting - IVF Clinical Trials

Lactobacillus for Luteal Phase Support

Start date: March 30, 2020
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effect of vaginal lactobacilli, a regulator of normal vaginal flora, on embryo implantation success during IVF / ICSI cycle follow-up.

NCT ID: NCT04002635 Withdrawn - Clinical trials for Polycystic Ovary Syndrome

Letrozole for Frozen Embryo Transfer (FET) in Patients With Polycystic Ovary Syndrome (PCOS)

LEFT
Start date: December 1, 2020
Phase: Phase 4
Study type: Interventional

To offer patients with oligomenorrhoea or amenorrhoea an alternative to frozen embryo transfer in an artificial cycle, endometrial preparation using letrozole may be a valuable option. Letrozole, a potent, reversible nonsteroidal aromatase inhibitor with relatively short half-life, can successfully induce ovulation without any adverse anti-estrogenic effects and thus without affecting the endometrium. The use of letrozole typically results in monofollicular growth and this reduces the effect of supraphysiological levels of estrogen on the endometrium and embryo. The purpose of this study is to compare a frozen-thawed embryo transfer in an artificial cycle with a letrozole-induced ovulatory cycle, specifically in PCOS patients. The primary outcome is early pregnancy loss.

NCT ID: NCT03989921 Completed - IVF Clinical Trials

Ovarian Reserve and Embryo Implantation

IRO
Start date: November 29, 2018
Phase:
Study type: Observational

Compare, in young patients with In vitro fertilization (IVF), the rate of embryo implantation by early culture transfer (J2-J3) between 2 groups of patients: "normo responders" vs. "poor responders".

NCT ID: NCT03974295 Not yet recruiting - Infertility Clinical Trials

The Impact of Vaginal Intercourse on Pregnancy Rates After Frozen Embryo Transfer

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

This study aims to evaluate whether allowing unprotected vaginal intercourse 24 hours after frozen embryo transfer will result in higher ongoing clinical pregnancy rates in comparison to having participants abstain from unprotected vaginal intercourse until pregnancy test (10-14 days after frozen embryo transfer).