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Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion — ETERNAL-LVO  

Ischemic Stroke Clinical Trial

Official title:
Extending the Time Window for Tenecteplase by Effective Reperfusion of peNumbrAL Tissue in Patients With Large Vessel Occlusion

Clinical Trial Summary

Patients presenting to the emergency department with an acute ischemic stroke due to a large vessel occlusion eligible for thrombectomy and target mismatch on computed tomography perfusion imaging within 24 hours of onset will be assessed determine their eligibility for randomization into the trial. If the patient gives informed consent they will be randomised using a central computerised allocation process to either standard of care (no intravenous thrombolytic treatment or intravenous alteplase 0.9mg/kg) or tenecteplase before undergoing intra-arterial clot retrieval. The trial is prospective, randomised, open-label, blinded endpoint (PROBE) design.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04454788
Study type Interventional
Source University of Melbourne
Contact Andrew Bivard, PHD
Phone +6193424424
Email abivard@unimelb.edu.au
Status Recruiting
Phase Phase 3
Start date August 1, 2020
Completion date December 1, 2025
View Details
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