Inter-Hospital Transfer to a Vascular Neurology Unit After Telethrombolysis

Ischemic Stroke Clinical Trial

— TRATT  

Official title:

Inter-Hospital Transfer to a Vascular Neurology Unit After Telethrombolysis in France Comté

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02902263
• Other study ID #: P/2015/248
• Status: Completed
• Start date: January 2014
• Est. completion date: January 2016

Study information

• Verified date: September 2016
• Source: Centre Hospitalier Universitaire de Besancon
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Early thrombolysis is essential in treating ischemic strokes. The time window for thrombolysis is limited to 4,5 hours after symptoms onset.

In the French region of Franche Comté, in order to reduce the thrombolytic delay, a telemedicine network was developed between the neurovascular reference unit (NVU) localised in the University Hospital of Besançon and the peripheral hospital centres. Patients may then be transported to the NVU immediately after the thrombolysis initiation.

The aim of our study was to assess the relevance of a systematic medicalization of transfer to the NVU of patients with stroke who were telethrombolyzed before.

It was a retrospective, monocentric and observational study conducted over 24 months, in Franche-Comte (France).

Description:

Stroke is a major health problem with increasing incidence. It represents the leading cause of disability and the third cause of death in France. There are two main types of stroke: ischemic (80%) or hemorrhagic (20%).

Early thrombolysis is essential in treating ischemic strokes. The time window for thrombolysis is limited to 4,5 hours after symptoms onset.

In the French region of Franche Comté, in order to reduce the thrombolytic delay, a telemedicine network was developed between the neurovascular reference unit (NVU) localised in the University Hospital of Besançon and the peripheral hospital centres. Patients may then be transported to the NVU immediately after the thrombolysis initiation.

The aim of our study was to assess the relevance of a systematic medicalization of transfer to the NVU of patients with stroke who were telethrombolyzed before.

It was a retrospective, monocentric and observational study conducted over 24 months, in Franche-Comte (France). Evaluation of neurological status was made with the Glasgow score (GCS) and National Institute of Health Stroke Score (NIHSS). The respiratory (SpO2; needs O2) and hemodynamic status (arterial blood pressure, heart rate) were assessed as well as the need for medical resuscitation at different times of the transport (thrombolysis, transfer, arrival at the Regional University Hospital Centre).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 79
• Est. completion date: January 2016
• Est. primary completion date: May 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patient with ischaemic stroke

• Emergency department admission between 01/01/2012 and 12/31/2013

• Telemedicine stroke consult

• Thrombolysis therapy

• Patient transfered to NVU after thrombolysis initiation

• Transfer staffed by a qualified physician

Exclusion Criteria:

• Transfer non staffed by a qualified physician

Related Conditions & MeSH terms

• Ischemic Stroke

Locations

Country	Name	City	State
France	CHRU Besancon	Besançon

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire de Besancon

Country where clinical trial is conducted

France, 

References & Publications (1)

Nenert E, Pretalli JB, Bouamra B, Puyraveau M, Fehner L, Labourey JM, Desmettre T. Transfert interhospitalier vers une unité de neurologie vasculaire des accidents vasculaires cérébraux ischémiques téléthrombolysés : pertinence d'une médicalisation systém

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Patient neurological status assessed by NIHSS score during transfer to NVU		one day
Primary	Patient neurological status assessed by Glasgow score during transfer to NVU		one day
Secondary	Patient respiratory status assessed by oxygen saturation		one day
Secondary	Patient hemodynamic status assessed by systolic and diastolic pressure		one day