Speech and Language Therapy After Stroke

Ischemic Stroke Clinical Trial

Official title:

Neurophysiological Measurement in Aphasia Treatment

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT00713050
• Other study ID #: 13785A
• Secondary ID: 5R01DC007488-05
• Status: Terminated
• Phase: N/A
• First received: July 9, 2008
• Last updated: June 10, 2013
• Start date: August 2007
• Est. completion date: January 2012

Study information

• Verified date: June 2013
• Source: University of Chicago
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Interventional

Clinical Trial Summary

Our overall goal is to advance the state of functional brain imaging in aphasia, and then to apply the method to an intensive, imitation-based treatment for non-fluent aphasia.

Description:

Detailed information will follow in the next progress report.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 34
• Est. completion date: January 2012
• Est. primary completion date: January 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

1. Single ischemic infarction in the MCA territory involving the cerebral cortex (confirmed by CT or MRI)

2. Aphasia

3. Visual attention and language comprehension sufficient to perform imitation fMRI tasks

4. Right handed (prior to stroke)

Exclusion Criteria:

Exclusions to the study are people with cardiac pacemakers, claustrophobia, neurosurgical clips, or cognitive impairments too severe to permit cooperation with cognitive tasks in an MRI scanner.

Study Design

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Ischemic Stroke

Intervention

Behavioral:
• Imitate Therapy
Imitation-based computer therapy

Locations

Country	Name	City	State
United States	Solodkin/Small Brain Circuits Laboratory	Irvine	California
United States	University of California Irvine	Irvine	California

Sponsors (3)

Lead Sponsor	Collaborator
University of Chicago	National Institute on Deafness and Other Communication Disorders (NIDCD), Rehabilitation Institute of Chicago

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes in scores on Western Aphasia Battery		Four months	No