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NCT00708838 Clinical Trial

Levels of Circulating T Cells Expressing VLA-1 Collagen Receptors

Ischemic Heart Disease Clinical Trial

Official title:
VLA-1 Receptors on Peripheral T Cells in Ischemic Heart Disease Patients

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00708838
Other study ID # SHEBA-02-2707-AA-CTIL
Secondary ID
Status Completed
Phase N/A
First received July 1, 2008
Last updated July 1, 2008
Start date January 2002
Est. completion date February 2007

Study information
Verified date July 2008
Source Sheba Medical Center
Contact n/a
Is FDA regulated No
Health authority Israel: Israeli Health Ministry Pharmaceutical Administration
Study type Observational

Clinical Trial Summary

The examination of the percentage of peripheral T cells carrying VLA-1 in ischemic heart disease patients. The hypothesis is that the percentage levels of cells carrying this integrin rise according to the severity of the ischemic heart disease.

Description:

Atherosclerosis is considered an inflammatory disease in which lymphocytes have an important role. The study was disigned to find out the changes in T cell levels carrying VLA-1 involvement in this process.

Recruitment information / eligibility
Status Completed
Enrollment 151
Est. completion date February 2007
Est. primary completion date January 2006
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- clinical diagnosis of acute MI for group 1

- clinical diagnosis of ACSl for group 2

- clinical diagnosis of Chronic Heart Disease for groups 3 and 4

- Chest pain but normal heart scan for group 5

Exclusion Criteria:

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Sheba Medical Center

Outcome
Type Measure Description Time frame Safety issue
Primary The differance in percentage of T cells in the 5 different groups involved. 2002-2006 No
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