Long-term Evaluation of Patients Receiving Bone Marrow-derived Cell Administration for Heart Disease — BMC registry  

Heart Failure Clinical Trial

Official title: Long-term Evaluation and Follow-up Care of Patients Receiving Intracoronary Bone Marrow-derived Cell Administration for Heart Disease

Status Active, not recruiting

Clinical Trial Summary

This study will provide follow-up information and care of patients who have undergone autologous intracoronary bone marrow cell administration at our institution. Patients are monitored for their response to treatment, progression of heart failure and coronary artery disease, and potential later occurring effects of the administered bone marrow cells.

Patients are eligible for this follow-up study if they have received their first intracoronary bone marrow cell administration for the treatment of cardiac disease at our institution from 2001 ongoing.

Participants are generally seen in the clinic at 12 months and 5 years after cell administration, in the meantime regular yearly telephone contacts are performed until 10 years after cell transplantation.

The detailed description contains the planned procedures that are performed during the clinical visits and, if necessary, at additional contacts.

Clinical Trial Description

In detail, the following procedures are performed during the clinical visits and, if necessary, at additional contacts:

• periodic physical examination and blood tests

• non-invasive imaging studies may include echocardiography and magnetic resonance imaging

• electrocardiogram at rest and during treadmill testing (may include spiroergometry testing)

• interrogation of implanted defibrillators / pacemakers for monitoring of arrhythmias ;

Related Conditions & MeSH terms

• Acute Myocardial Infarction
• Cardiomyopathies
• Cardiomyopathy, Dilated
• Dilated Cardiomyopathy
• Heart Diseases
• Heart Failure
• Infarction
• Ischemic Cardiomyopathy
• Myocardial Infarction

• NCT number: NCT00962364
• Study type: Observational
• Source: Johann Wolfgang Goethe University Hospital
• Status: Active, not recruiting
• Start date: October 2001
• Completion date: December 2021