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Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption

Irritable Bowel Syndrome With Diarrhea Clinical Trial

Official title:
Randomized, Double Blinded, Placebo Controlled Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption

Clinical Trial Summary

To compare with a randomized trial (n=15 per treatment group), effects of colesevelam and placebo treatment, on colonic transit, bowel functions, permeability and tight junction expression in rectosigmoid mucosa of IBS-D with Bile Acid Malabsorption.

Clinical Trial Description

Compare the effects of Colesevelam versus the placebo on diabetic subjects with chronic diarrhea. In this study, diabetic subjects will get either the Colesevelam or the placebo, not both.

The plan is to have about 30 subjects complete this study at Mayo Clinic. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03270085
Study type Interventional
Source Mayo Clinic
Contact
Status Completed
Phase Phase 2
Start date December 7, 2017
Completion date May 31, 2019
View Details
See also
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