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Intubation Complication clinical trials

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NCT ID: NCT06247969 Completed - Clinical trials for Intubation Complication

Cone Beam Computed Tomography For Appropriate Nostril Selection for Nasotracheal Intubation

Start date: December 19, 2023
Phase:
Study type: Observational

Design: Nasotracheal intubation is a standard blind procedure associated with various complications. Selection of the appropriate nostril is crucial in preventing most of these complications. The investigators aimed to evaluate the contribution of CBCT findings in selecting the proper nostril for nasotracheal intubation. Methods: This prospective observational study outlines the protocol for research conducted at the Selçuk University Faculty of Dentistry. Scope of the Research: The study encompasses patients undergoing dental surgery under general anesthesia at the Selçuk University Faculty of Dentistry. 1. Participant Selection: ASA I-II patients will be included in the study. Patients with structural abnormalities in the maxillo-mandibular anatomy, limited mouth opening, comorbidities such as rheumatoid arthritis, and a history of epistaxis will be excluded from the study. 2. Anesthesia Method: General anesthesia induction will be performed with intravenous (IV) propofol, IV rocuronium bromide, and IV fentanyl. Transition to nasotracheal intubation will follow adequate mask ventilation, and the preferred nostril will be determined through a simple occlusion test. 3. Data Collection: Demographic data, accompanying illnesses, medications used, and various parameters related to nasotracheal intubation will be recorded. The anesthetist performing nasotracheal intubation will be blinded to CBCT data, and the evaluation of data will be conducted jointly by the anesthetist and Radiology specialist after data collection from all patients is complete. 4. Exclusion Criteria: Unsuccessful nasotracheal intubation, difficult mask, and/or difficult intubation. 5. Implementation and Evaluation: Anesthesia procedures and CBCT evaluations will be carried out by experienced specialists. 6. The objective of this study is to evaluate the use of preoperative measurements of the nasal cavity from CBCT images in selecting the appropriate nostril for nasotracheal intubation under general anesthesia. The statistical tests to be employed are the chi-squared test and independent samples t-test.

NCT ID: NCT06065956 Completed - Clinical trials for Intubation Complication

Comparison of Hemodynamic Changes With Morphine Versus Esmolol During Induction of Anaesthesia

Start date: August 28, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Comparing hemodynamic changes with morphine versus esmolol as an adjuvant agent during induction of Anaesthesia

NCT ID: NCT05762068 Completed - Critical Illness Clinical Trials

Expert Consensus Statements for the Management of a Physiologically Difficult Airway Using the Delphi Method (PDADelphi)

PDADelphi
Start date: April 1, 2023
Phase:
Study type: Observational

The aim of this study is to review/identify the existing definition and management strategies for a physiologically difficult airway (PDA), to generate expert consensus on the various aspects of managing a patient with a PDA using the Delphi method, and to provide guidance to clinicians worldwide on safe tracheal intubation practices in patients with PDA to help improve patient outcomes.

NCT ID: NCT05672329 Completed - Anesthesia Clinical Trials

Functional Residual Capacity Under Apnoeic Oxygenation With Different Flow Rates in Children

FUTURE
Start date: January 9, 2023
Phase: N/A
Study type: Interventional

During induction of general anaesthesia physiological breathing stops and needs to be artificially established with facemask ventilation, and finally tracheal intubation or placement of a supraglottic airway. During the airway management, when lungs are not or only poorly ventilated, there is a risk for atelectasis. These atelectasis can contribute to respiratory adverse events (e.g. pulmonary infection or respiratory insufficiency) during or after general anaesthesia. High-flow nasal oxygen (HFNO) is the administration of heated, humidified and blended air/oxygen mixture via a nasal cannula at rates ≥ 2 L/kg/min. HFNO used during airway management (i.e. intubation) can extend the tolerance for apnea, the time from end of physiological breathing until artificial ventilation is established. The main objective of this study is thus to investigate the variations of poorly ventilated lung units (i.e., silent spaces) as a surrogate for functional residual capacity measured by electrical impedance tomography to dynamically assess atelectasis formation and regression under apnoeic oxygenation with different flow rates.

NCT ID: NCT05668299 Completed - Clinical trials for Mechanical Ventilation Complication

Determining the Appropriate Setting of an Automated Secretion Removal Technology (TrachFlush)

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Using a new device, the TrachFlush, the aim of this pilot study is to investigate whether secretions can be removed at the patient's current ventilator settings, or whether pressures and durations considered at the maximal end of clinical practice are required, so as to push secretions around the cuff. The study is a pilot study to investigate the settings required to ensure clinical efficacy of the technology, prior to large scale clinical studies.

NCT ID: NCT05633069 Completed - Clinical trials for Intubation Complication

Interest of Instantaneous Fluctuations of Pupillary Diameter for Pain Evaluation in Intensive Care Sedated Patients.

Start date: November 1, 2022
Phase:
Study type: Observational

New pain assessment parameter, called the Variation Coefficient of Pupillary Diameter (VCPD) described. This parameter allows evaluating the pain of patients during uterine contractions in obstetrical labor, and postoperatively in recovery room. This parameter also allows evaluating the level of pain in Intensive Care Unit (ICU), in intubated or tracheotomized patients moderately sedated (Riker score 3 or 4).

NCT ID: NCT05607836 Completed - Clinical trials for Intubation Complication

IntuBrite Versus Macintosh for Endotracheal Intubation in Out of Hospital Cardiac Arrest

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

a randomized, parallel, non-blinded trial in a single Emergency Mdeical Service in Poland within a group of 34 ground ambulances crews, comparing time and first pass success (FPS) for endotracheal intubation (ETI) in DL using the IntuBrite® (INT) and Macintosh laryngoscope (MCL) during cardiopulmonary resuscitation (CPR). intubations will be performed using INT and MCL based on an intention-to-treat analysis. The FPS time of the ETI attempt will be analysed. First attempt success will be counted.

NCT ID: NCT05502120 Completed - Obesity, Morbid Clinical Trials

A Comparison of Vie-Scope and Macintosh Blade Laryngoscopes in Morbidly Obese.

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Macintosh laryngoscope is still considered a standard for tracheal intubation, however, visualization of the glottis may be inadequate mainly in morbidly obese patients. The Vie Scope is a novel type of laryngoscope consisting of a straight, shielded, illuminated tube that offers intubation via a bougie using the paraglossal technique. In this prospective, non-randomized study, we tested the research hypothesis that the use of Vie Scope may improve visualization of the larynx in comparison with the Macintosh blade.

NCT ID: NCT05383417 Completed - Dysphagia Clinical Trials

No Post Intubation Laryngeal Symptoms

No-PILS
Start date: November 8, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to test a novel endotracheal tube support device that reduces pressure of the tube on the voice box for prevention of post intubation laryngeal symptoms including sore throat, change in voice and trouble swallowing.

NCT ID: NCT05303948 Completed - Clinical trials for Intubation Complication

Evaluation of Two Positions for Free Floating Tracheal Intubation in Weightlessness

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

In a non-randomized, controlled, cross-over simulation study, the investigators evaluated and compared intubation performance of trained operators, using either a conventional laryngoscope in an ice-pick position or a video laryngoscope in a free-floating classic position, in weightlessness and in normogravity. Data were analyzed with the generalized linear mixed-effects models. Primary endpoint was the success rate of tracheal intubation. Time to intubation and the confidence score into the success of tube placement were also recorded as secondary endpoints.