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Intraocular Pressure clinical trials

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NCT ID: NCT06450587 Recruiting - Clinical trials for Intraocular Pressure

Intraocular Pressure Data Collection With Tonometers

Start date: May 31, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to collect a comprehensive dataset of intraocular pressure values for developing a measurement algorithm for the new hand-held rebound tonometer device. The measurement algorithm shall fulfill the requirements of ANSI Z80.10:2014 standard. The study population is adults (age ≥ 18 years). The intraocular pressure of the participants will be measured with four different tonometers.

NCT ID: NCT06275308 Recruiting - Clinical trials for Intraocular Pressure

Effect of Raised End-Tidal pCo2 on Choroidal Volume

Start date: February 27, 2023
Phase: N/A
Study type: Interventional

This study is to investigate the relationship between arterial carbon dioxide (CO2) concentration and vitreous pressure on the choroidal volume by integrated intraoperative OCT imaging under eye exams under anesthesia.

NCT ID: NCT06016712 Recruiting - Clinical trials for Intraocular Pressure

The Effect of Labor on Intraocular Pressure Fluctuation in Healthy Eyes

ELIPFHE
Start date: August 8, 2023
Phase: N/A
Study type: Interventional

Glaucoma is a multifactorial disease, an important risk factor of which is increased intraocular pressure. Fluctuations in intraocular pressure are often associated with vaginal birth, although intraocular pressure during active pushing during stage II has never been measured.. The study will be conducted on a group of patients with healthy eyes on patients who have completely fine vision or have a small refractive error and are accustomed to wearing contact lenses. The measurement of intraocular pressure itself will be carried out using SENSIMED Triggerfish contact lenses, which measure pressure every 5 minutes for 30s. This period roughly corresponds to the duration of 1-2 contractions. Inclusion in the study will be offered to patients in the 35th to 37th week of pregnancy. Prior to measurement patients will be sent to an eye clinic for a detailed examination of both eyes, which includes measuring intraocular pressure. Subsequently, pregnancy checks will take place according to the standard scheme and in the standard scope. At the onset of uterine contractions, an ophthalmologic consultant will be called, which will measure intraocular pressure between contractions using the Tonopen device and put on SENSIMED Trigerfish contact lenses in combination with a local anesthetic. The patient will have these lenses until the end of the third stage of labor, i.e. 2 hours after the birth, when the lenses are removed. In the second stage of labor, continuous monitoring by a cardiotocograph will take place. Subsequently, the obtained data from the cardiotocograph and contact lenses will be evaluated and compared by a team of ophthalmologists and gynecologists, where the investigators will be able to assess the individual fluctuations in intraocular pressure depending on the individual contractions. The aim of the study is to demonstrate or disprove the risks to the glaucoma patient due to increased intraocular pressure during active pushing in combination with uterine contraction.

NCT ID: NCT05753137 Recruiting - Glaucoma Clinical Trials

Acupuncture as Adjuvant Therapy for Glaucoma - Protocol for a Randomized Controlled Trial

Start date: June 28, 2023
Phase: N/A
Study type: Interventional

This clinical trial used acupuncture as an adjunctive treatment for glaucoma patients. A randomized, controlled trial involving 50 subjects will be conducted and observed for 12 weeks to evaluate the clinical efficacy of acupuncture. This study aims to provide a reference for future clinical treatment guidelines.

NCT ID: NCT05466526 Recruiting - Clinical trials for Primary Open Angle Glaucoma

Microinvasive Glaucoma Surgery -The Lowering Effect of Intraocular Pressure on Glaucoma Patients With High Frequency Deep Sclerotomy

HFDS
Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Highlights the high-frequency deep sclerotomy (HFDS) as a promising ab-interno surgery in primary open-angle glaucoma (POAG) patients and evaluates the efficacy and safety of the procedure.

NCT ID: NCT05352906 Recruiting - Glaucoma Clinical Trials

Accuracy of Handheld and Non-contact Tonometry

Start date: April 20, 2022
Phase: N/A
Study type: Interventional

Monitoring the intraocular pressure (IOP) is one of the most important tests used in follow-up among glaucoma suspects and confirmed glaucomatous patients.

NCT ID: NCT05288192 Recruiting - Cataract Clinical Trials

Changes After Suprachoroidal Injection.

Start date: February 15, 2022
Phase: N/A
Study type: Interventional

Changes after suprachoroidal injection are analyzed for statistical analysis.

NCT ID: NCT04628663 Recruiting - Clinical trials for Intraocular Pressure

Effects of Dexmedetomidine on Intraocular Pressure During Scheduled Spine Surgeries

Start date: March 20, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to examine the effects of intraoperative systemic use of dexmedetomidine on the intraocular pressure (IOP) in patients undergoing spine surgeries in a prone position under general anesthesia.

NCT ID: NCT04485897 Recruiting - Clinical trials for Intraocular Pressure

Self-monitoring of the Intraocular Pressure Versus Hospital-based Diurnal Monitoring

Start date: November 26, 2020
Phase: N/A
Study type: Interventional

Glaucoma remains the leading cause of irreversible blindness worldwide. Glaucoma represents a group of diseases that lead to optic nerve damage and corresponding deterioration of the visual field. Elevated intraocular pressure remains the most important risk factor. Interestingly, glaucomatous damage sometimes occurs despite seemingly normal intraocular pressure. Recent studies suggest pressure peaks, which are missed under the current practice of spot intraocular measurements during office hours. In order to detect pressure peaks diurnal measurements are mandatory. Costly in-hospital diurnal measurements are the current standard. The primary study objective is to verify that self-tonometry at home can provide valuable information when looking for pressure peaks in patients with glaucoma.

NCT ID: NCT04281017 Recruiting - Oncology Clinical Trials

Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients

Start date: November 10, 2020
Phase: Phase 4
Study type: Interventional

Steep Trendelenburg positioning and insufflation of the abdominal cavity have shown to increase intra ocular pressure. Different anesthetic techniques can alter intra ocular pressure and a small pilot study showed decrease in Intraocular Pressure (IOP) in robotic case in steep Trendelenburg with IV anesthetics (TIVA). We want to quantify the degree of change in Intraocular Pressure (IOP) in female patients undergoing robotic procedures for cancer. We want to detect the difference in increase of pressure with total IV anesthesia versus conventional balanced anesthesia