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Intraocular Pressure clinical trials

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NCT ID: NCT03400137 Recruiting - Clinical trials for Intraocular Pressure

IOP Elevation Study

Start date: March 7, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to improve understanding of the pathophysiologic process that leads to the development of glaucamotous damage. The mechanism by which vision loss in glaucoma occurs is still unknown, but it is clear that increased intraocular pressure (IOP) is a major risk factor. It is also thought that the LC is a site of primary damage during pathogenesis of the disease. This prospective study with determine the in-vivo mechanical response to IOP modulation at the level of the ONH and LC.

NCT ID: NCT03344432 Recruiting - Children, Only Clinical Trials

Correlation Intraocular Pressure With Intracranial Pressure

IOPICPTBI
Start date: June 10, 2015
Phase: N/A
Study type: Observational [Patient Registry]

Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend). Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values.

NCT ID: NCT03057301 Recruiting - Glaucoma Clinical Trials

Assessment of Home Tonometry in Glaucoma

Start date: April 1, 2016
Phase: N/A
Study type: Observational

Worldwide, glaucoma is the most common cause of irreversible blindness. The major risk factor is raised pressure within the eye (intraocular pressure, IOP). IOP is typically measured using Goldman applanation tonometry (GAT). This involves instilling anaesthetic eye drops and using a probe to contact the cornea and obtain a pressure measurement. A major disadvantage of GAT is that only limited numbers of pressure measurements can be obtained, whereas IOP is known to vary throughout the day and in ¾ of people is highest during the night. The result is that clinicians have poor understanding of patient's 24 hour IOPs and the effect that this might have on their glaucoma. This is a serious limitation as the treatment of glaucoma depends on lowering IOP. Recently a new device has become available, designed specifically for home IOP monitoring. The iCare HOME tonometer is a CE marked commercial device (http://www.icaretonometer.com/products/icare-home-tonometer/) that can be used to gain insight into 24-hour IOP fluctuations. We wish to determine the feasibility of home IOP monitoring using this device. The iCare HOME tonometer depends on the patient performing self-tonometry. Testing one's own IOP may be technically difficult and it is likely that large numbers of patients will struggle with this.

NCT ID: NCT02697825 Recruiting - Clinical trials for Intraocular Pressure

Intraocular Pressure Versus Optic Nerve Sheath Diameter

Start date: September 2015
Phase: N/A
Study type: Interventional

This study involves observing and comparing Intraocular Pressure and Optic Nerve Sheath Diameter in steep trendelenburg position. Both observations will be done in same patient over the surgical duration.

NCT ID: NCT01801774 Recruiting - Inflammation Clinical Trials

Efficacy Comparison Study of Steroids to Control Post-operative Inflammation

Start date: May 2012
Phase: Phase 4
Study type: Interventional

Phacoemulsification is a quick method with less complication for cataract surgery. Due to the use of ultrasonic energy, it produced more post-operative inflammation than other methods. Many routes of steroid had been used to control post-operative inflammation. The investigators here compare the efficacy of single depot steroid subtenon injection (20-mg triamcinolone) with four-time-a-day steroid eye drop (0.1% dexamethasone) in controlling inflammation after uneventful phacoemulsification.