Non-invasive ONSD-based Neuromonitoring in a Neurointensive Care Setting — ONSDDynamics  

Subarachnoid Hemorrhage Clinical Trial

Official title: Non-invasive Neuromonitoring Through Point-of-care Determination of ONSD and Assessment of Dynamic Properties of the Optic Nerve Sheath in a Neurointensive Care Setting

Status Not yet recruiting

Clinical Trial Summary

Intensive care patients with established invasive intracranial neuromonitoring due to neurotrauma are subjected to a repeated non-invasive sonographic recording of the optic-nerve-sheath-diameter (ONSD). The recorded images are analyzed through a machine-learning-algorithm and an experienced ultrasound operator. Results are correlated to the parallel recorded intracranial pressure (ICP). The study aims to establish ONSD as a supplementary for raised ICP.

Clinical Trial Description

During the intensive care stay, patients with implemented invasive intracranial pressure monitoring will have sonographic recording of the optic nerve sheath (video clip) with a parallel recording of the underlying ICP. The obtained image material is then i) analyzed by a machine-learning algorithm and ii) manually by 2 blinded differently experienced examiners (expert, novice) with respect to the ONSD. For the manual procedure, three individual measurements are made for each eye and the mean value is determined. Subsequently, the measured values of the two examiners and the automated procedure are correlated with the ICP recorded during the sonographic examination. ;

Related Conditions & MeSH terms

• Brain Injuries, Traumatic
• Hemorrhage
• Intracranial Hypertension
• Subarachnoid Hemorrhage
• Trauma, Brain

• NCT number: NCT05818371
• Study type: Interventional
• Source: University Hospital Tuebingen
• Contact: Jonas Tellermann, MD
• Phone: +4970712968685
• Email: Jonas.Tellermann@med.uni-tuebingen.de
• Status: Not yet recruiting
• Phase: N/A
• Start date: May 1, 2023
• Completion date: March 2024