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Intracranial Embolism clinical trials

View clinical trials related to Intracranial Embolism.

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NCT ID: NCT06309069 Recruiting - Clinical trials for Calcified Cerebral Embolism

Calcified Cerebral Embolism: a Descriptive Study in a Large Single Center Cohort

CCE Cohorte
Start date: April 16, 2024
Phase:
Study type: Observational

Calcified cerebral embolism (CCE) is a relatively rare but underdiagnosed cause of infarction. CCE diagnosis is made by CT. Radiological characteristics of CCE have been reported in small case series. The aim of this study was to describe clinical and radiological characteristics of CCE in a large number of patients, and to compare patients with different radiological CCE characteristics.

NCT ID: NCT05671276 Recruiting - Atrial Fibrillation Clinical Trials

Efficacy of Different Anti-Thrombotic Strategies on the Incidence of Silent Cerebral Embolism After Percutaneous Left Atrial Appendage Occlusion

Start date: February 1, 2022
Phase: Phase 4
Study type: Interventional

The primary objective of this investigation is to compare the efficacy of two different antithrombotic strategies after percutaneous LAA occlusion with a Watchman device on the prevention of silent cerebral embolism.

NCT ID: NCT04704258 Completed - Clinical trials for Aortic Valve Stenosis

NAUTILUS CE-mark Trial of the FLOWer Cerebral Embolic Protection Device

NAUTILUS
Start date: May 3, 2021
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to assess the safety, performance, and treatment effect of the use of the AorticLab FLOWer System, in preventing cerebral thromboembolic complications in patients with indication for a TAVI (Transcatheter Aortic Valve Implant).

NCT ID: NCT04408716 Completed - Atrial Fibrillation Clinical Trials

Risk of Asymptomatic Cerebral Embolism During AF Ablation With AI-HPSD Strategy Versus Standard Settings

Start date: June 17, 2020
Phase: N/A
Study type: Interventional

The purpose of this prospective randomized controlled study is to evaluate the risk of asymptomatic cerebral embolism during catheter ablation of atrial fibrillation (AF) with AI-HPSD strategy versus standard radiofrequency ablation settings, with the diagnosis of asymptomatic cerebral embolism is determined by brain high-resolution diffusion-weighted magnetic resonance imaging technique.

NCT ID: NCT03802760 Completed - Cerebral Embolism Clinical Trials

Cerebral Microembolism in Cardiology

ZEMEK
Start date: October 24, 2018
Phase:
Study type: Observational

During different interventional cardiology procedures we aim to identify cerebral microemboli load. Further we aim to differentiate the quality and the quantity of cerebral microemboli.We will measure cerebral microemboli in different interventional phases, e.g. during valve deployment, rapid pacing, post-implantation.

NCT ID: NCT03218293 Completed - Clinical trials for Acute Ischemic Stroke, Cerebral Embolism and Thrombosis

Thrombolysis and RIPC in Acute Ischemic Stroke

tripcais
Start date: August 1, 2017
Phase: N/A
Study type: Interventional

Remote ischemic postconditioning (RIPC) is suggested to protect the cerebral cell against ischemia in various settings. However, the effect of RIPC in patients with acute ischemic stroke who undergo thrombolysis has yet to be examined. In this single-center, randomized controlled trial, we examined the effect of RIPC on the resolution of nerve function deficient in response to thrombolysis. Patients in the RIPC group had five cycles of 5-min cuff inflation followed by 3-min deflation to the bilateral upper arm after thrombolysis. The primary endpoint was the recovery of nerve function deficient assessed by National Institutes of Health Stroke Scale(NIHSS), Activities of Daily Living(ADL), Modified Rankin Scale(mRS), CT cerebral perfusion imaging (CTP) and CT angiography(CTA). Secondary endpoints included the following: angiogenesis assessed by the level of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF).

NCT ID: NCT03098732 Suspended - Stroke, Acute Clinical Trials

Magnetically Enhanced Diffusion for Acute Ischaemic Stroke (MEDIS) Trial

MEDIS
Start date: March 22, 2017
Phase: N/A
Study type: Interventional

The objective of the MEDIS study is to determine if subjects experiencing an Acute Ischaemic Stroke due to large vessel occlusion, treated with IV tPA combined with the MED procedure have a greater likelihood of recanalisation 30-90 minutes after the completion of tPA infusion than subjects treated with IV tPA (plus sham device). Safety of the MED System Procedure will be evaluated by the incidence of symptomatic PH-2 haemorrhagic transformation within 24 hours following the procedure. Lastly, a health economics study will be conducted to estimate health care costs for each treatment.

NCT ID: NCT03008798 Not yet recruiting - Clinical trials for Occlusion and Stenosis of Unspecified Cerebral Artery

Prevention for the Restenosis of Intracranial Artery Stent Implantation Treated With Herbal Medicine C117

PRISIT
Start date: January 2017
Phase: Phase 2
Study type: Interventional

Prevention for the Restenosis of Intracranial artery Stent Implantation Treated with herbal medicine C117--PRISIT Trial

NCT ID: NCT03001960 Not yet recruiting - Clinical trials for Aortic Valve Stenosis

Dual AntiPlatelet Therapies for Prevention of Periinterventional Embolic Events in TAVI

DAPT-TAVI
Start date: March 2017
Phase: Phase 3
Study type: Interventional

TAVI is increasingly adopted as standard treatment for many subgroups of patients with aortic stenosis. However, due to a lack of data there is yet no TAVI-specific guidance regarding the optimum periinterventional drug regimen. The study evaluates the effect of dual antiplatelet pretreatment on periinterventional embolic cerebral lesions and bleeding complications in patients undergoing transfemoral aortic valve implantation (TF-TAVI).

NCT ID: NCT02955004 Completed - Clinical trials for Intracranial Embolism

Electrical Cardioversion of Recent Onset Atrial Fibrillation - Silent Thromboembolic Events, Reverse Atrial Remodeling

ECAF-STAR
Start date: February 2015
Phase:
Study type: Observational

The purpose of this study is to study the effects of transthoracic electrical cardioversion for restoration of sinus rhythm in patients who present with recent onset atrial fibrillation, with regard to new silent cerebral thrombo-embolic lesions and cognitive function, as well as electrical and functional/structural reverse remodelling, and its effects on inflammatory changes / specific cardiac biomarkers, vasoactive peptides, coagulation activity, and active fibrinolysis.