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Intra-dialytic Hypotension clinical trials

View clinical trials related to Intra-dialytic Hypotension.

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NCT ID: NCT03870594 Not yet recruiting - Clinical trials for Intra-dialytic Hypotension

IDH in Diabetic Haemodialysis Patients and Association With Dialytic Age

Start date: April 2019
Phase:
Study type: Observational

Intradialytic hypotension (IDH ) is a serious and the most frequent complication of hemodialysis of the hemodialysis .Diabetes is associated with autonomic neuropathy which contribute to intradialytic hypotension

NCT ID: NCT03856151 Completed - Clinical trials for Hemodialysis-Induced Symptom

To Evaluate the Effects of Heating Device (Electronic Moxibustion) in Patients With Intradialytic Hypotension

Start date: April 17, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effects of heating device among otherwise stable patients with intradialytic hypotension

NCT ID: NCT03397992 Completed - Acute Kidney Injury Clinical Trials

Low Dialysate Temperature During SLED

Start date: January 16, 2017
Phase: N/A
Study type: Interventional

Objectives: This study is evaluating the hemodynamic effects of lowering the dialysate temperature in acute kidney injury (AKI) patients submitted to sustained low efficiency dialysis (SLED) in a single large center. Methods: Participants will be randomly assigned to two treatment groups. One group will be started treatment with low temperature (set point 5 on the machine which is around 35°C) for one treatment and then alternate between high and low temperatures for a maximum of 8 treatments. The other group will be started with high temperature (set point 9 on the machine which is around 37°C) for the first treatment then alternate between high and low temperatures for a maximum of 8 treatments. Each participants will need at least two treatments, one with each temperature to be included in the analysis. The investigators will be looking for the number of events during a SLED treatment. Events will be defined as drop in systolic blood pressure ≥ 20 mmHg or drop in mean arterial pressure (MAP) of ≥10 mmHg, requirement of resuscitation with IVF after initiation of SLED, initiation or increase requirement of vasoactive drugs.

NCT ID: NCT03144817 Completed - Hypertension Clinical Trials

Dialysate Sodium Lowering Trial

DeSaLT
Start date: April 26, 2017
Phase: Phase 2
Study type: Interventional

This is a pilot randomized clinical trial in which patients treated with 3X per weekly conventional hemodialysis will be treated to a dialysate sodium 135 mEq/L vs. 138 mEq/L and followed for safety and tolerability, effects on BP and volume.

NCT ID: NCT02145260 Completed - Clinical trials for Intra-dialytic Hypotension

Trial of Dialysate Sodium in Chronic Hospitalized Hemodialysis Patients

Start date: July 1, 2014
Phase: N/A
Study type: Interventional

Intra-dialytic hypotensive (IDH) events can be defined as an abrupt decline in blood pressure that cause symptoms and/or require an intervention. They are common, affecting up to one third of maintenance HD sessions. Detrimental associations include: development of myocardial stunning, cerebral hypo-perfusion, vascular access thrombosis and greater mortality. Rapid solute removal by HD generates temporary osmotic gradients between the intra-vascular and intra-cellular compartments, promoting trans-cellular fluid movement and resultant hypotension. Manipulation of osmotic gradients, e.g. using higher dialysate sodium (DNa), may ameliorate excess SBP decline during HD. This study aims to assess the effects of higher (142 mmol/L) versus lower (138 mmol/L) dialysate sodium (DNa) use in adult chronic hemodialysis patients admitted to hospital on intra-dialytic blood pressure and biomarkers of cardiac ischemia. The investigators will randomly assign subjects to higher versus lower DNa during their hospital stay, up to a maximum of six HD sessions.

NCT ID: NCT01520207 Completed - Clinical trials for Intra-dialytic Hypotension

Mannitol - Potential Role in Hemodialysis Initiation for Reduction of Intra-dialytic Hypotension

Start date: May 2012
Phase: Phase 2
Study type: Interventional

Kidney failure can result from a variety of conditions and can be temporary or permanent. Hemodialysis is available as a replacement treatment to perform the work that the kidneys normally do. However, the dialysis procedure can be associated with rapid changes in the composition of the blood - this may lead to changes in blood pressure and in turn reduced blood supply to important parts of the body. We aim to investigate if giving a medicine (called mannitol) during dialysis may be able to reduce the frequency of these low blood pressure events.

NCT ID: NCT00448071 Recruiting - Clinical trials for End Stage Renal Disease

Pharmacokinetic and Pharmacodynamic Effects of MTR107 in End-Stage Renal Disease (ESRD) Patients

Start date: May 2006
Phase: Phase 2
Study type: Interventional

MTR107 effect on blood pressure throught the dialysis procedure and its ability to prevent Intra dialytic Hypotension