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Intervertebral Disc Degeneration clinical trials

View clinical trials related to Intervertebral Disc Degeneration.

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NCT ID: NCT05844358 Completed - Clinical trials for Degenerative Disc Disease

Cortical Bone Trajectory With Patient Guide

MySpine MC
Start date: June 26, 2019
Phase:
Study type: Observational

The use of patient specific guides with proper preoperative planning, following a cortical bone trajectory technique, should guarantee a successful surgery and benefit of less invasive technique. This study intends to measure the safety and efficacity of MySpine MC patient-specific guide system, when used according to its general indication of use and following the surgical technique suggested by the manufacturer

NCT ID: NCT05641857 Completed - Disc Degeneration Clinical Trials

Lumbar Spine on MRI and Low Back Pain in Elite Cross-country Skiers

Start date: September 1, 2022
Phase:
Study type: Observational

The investigators will examine the prevalence of low-back pain and disc degeneration among Finnish elite skiers between 16 and 35 years of age and compare these findings with the data collected among healthy volunteers studied between 1994-2021.

NCT ID: NCT05601739 Completed - Low Back Pain Clinical Trials

Interleukin-1β (rs 1143627 T/C) Gene Polymorphism May Increase the Risk of Developing LDD in Turkish Population

Start date: April 8, 2019
Phase:
Study type: Observational

This study aims to show the association between the Interleukin-1β (rs 1143627 T/C) gene polymorphism and the patient's pain level, radiological features, functional disability, and spinal flexibility.

NCT ID: NCT05574543 Completed - Clinical trials for Degenerative Disc Disease

A Phase I/II Study of AGA111 for Lumbar Interbody Fusion in Patients With Degenerative Disc Disease

Start date: December 1, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

The objectives of the study are to evaluate the safety and preliminary efficacy of a single administration of AGA111 for lumbar interbody fusion in patients with degenerative disc disease.

NCT ID: NCT05566704 Completed - Clinical trials for Degenerative Disc Disease

Retrospective Modulus ALIF Study

Start date: August 18, 2022
Phase:
Study type: Observational

The primary objective of this study is to evaluate the safety and performance of the Modulus ALIF System in patients undergoing anterior lumbar interbody fusion (ALIF) as measured by reported complications, radiographic outcomes, and patient-reported outcomes.

NCT ID: NCT05414604 Completed - Clinical trials for Vertebral Disc Degenerative Disease

Calculating the Volume of the Paravertebral Space

Start date: June 15, 2022
Phase:
Study type: Observational

Volume of the paravertebral spaces of the tharic and lumbar regions will be measured.

NCT ID: NCT05315375 Completed - Disc Degeneration Clinical Trials

Post-trauma Lumbar Vertebral Body Reconstruction Using Expandable Cages

Start date: January 2, 2010
Phase:
Study type: Observational

INTRODUCTION The expandable cage technology is not new, but several questions remain under-studied. Among them, there are the sagittal balance, the subsidence and the adjacent disc degeneration. Moreover, assessment of the correction and kyphosis regardless of the physiological angles can possibly lead to calculation bias. The objective of this study was to assess the extent to which the functional outcomes were correlated to the quality of the reduction, within a homogeneous series of lumbar vertebral body reconstruction with expandable cages for trauma. MATERIAL AND METHODS Twenty-seven patients with a mean follow-up of 3.9 years were retrospectively analyzed. The Oswestry Disability Index (ODI) was the main outcome and its association with other variables was sought. The local kyphosis and the regional traumatic angle using Stagnara's physiological angles were measured. The lumbar lordosis (LL) was compared to the Pelvic Incidence (PI). The subsidence of the cage and the adjacent disc degeneration (using the UCLA grading score) were quantified. Bone quality was assessed through the Hounsfield Unit of the vertebral body.

NCT ID: NCT05223439 Completed - Neuropathic Pain Clinical Trials

Balance and Gait on Neuropathic Pain Due to Lumbar Disc Degeneration

Start date: January 5, 2022
Phase:
Study type: Observational

Chronic lumbar neuropathic pain, characterized by pain, numbness, tingling and muscle weakness in the lower extremities, is one of the most common neuropathic pain syndromes. It is expected that balance and gait disturbances will occur as a result of motor and sensory problems in patients with neuropathic pain due to lumbar disc degeneration. However, as far as the investigators know, there is no study in the literature describing the effects of neuropathic pain due to lumbar disc degeneration on balance and gait. Therefore, the aim of our study; To examine the effects of neuropathic pain due to lumbar disc degeneration on balance and gait.

NCT ID: NCT05059249 Completed - Low Back Pain Clinical Trials

Effects of Mechanical Versus Manual Traction in the Management of Low Back Pain.

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

This study compared the effects of mechanical and manual traction on pain, disability and lumbar spinal curvature in patients with discogenic low back pain

NCT ID: NCT04876586 Completed - Clinical trials for Degenerative Disc Disease

The SPINUS I Study: Spinal Fusion for a Single Level SPECT/CT Positive Lumbar Degenerative Disc Disease

Start date: January 1, 2018
Phase:
Study type: Observational

The aim of the present study is to find out whether fusion of a sinlge level SPECT/CT positive degenerative disc disease leads to a significant improvement of pain and disability.