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Intervertebral Disc Degeneration clinical trials

View clinical trials related to Intervertebral Disc Degeneration.

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NCT ID: NCT04735185 Suspended - Clinical trials for Chronic Low Back Pain

Stem Cells vs. Steroids for Discogenic Back Pain

Start date: September 30, 2025
Phase: N/A
Study type: Interventional

This is a randomized, comparative-effectiveness study comparing intradiscal autologous stem cells (from bone marrow aspirate) to intradiscal corticosteroid for the treatment of chronic discogenic low back pain (LBP). The primary objective of this study is to determine whether intradiscal autologous stem cells (from bone marrow aspirate) is more effective than intradiscal steroids for the treatment of chronic discogenic low back pain (LBP). Participants in this study will be randomized to receive up to intradiscal stem cell injections at 1 or 2 discs with cells harvested from a bone marrow aspirate drawn from participants' iliac crest, or an equal volume (2 mL) of intradiscal steroids and local anesthetic injected into the discs. In order to identify the painful disc(s), discography may be used at the discretion of the provider. Both treatments are frequently used as part of clinical care (i.e. there is no placebo group).

NCT ID: NCT03871400 Suspended - Clinical trials for Disc Degeneration;Cervical

The NanoStrand Clinical Study

Start date: November 18, 2018
Phase: N/A
Study type: Interventional

A prospective, multi-center, randomized, self-controlled, single-blinded, clinical study evaluating the NanoMetalene implant as compared to the PEEK and allograft implants in ACDF for the treatment of cervical degenerative disc disease (DDD).

NCT ID: NCT03726190 Suspended - Clinical trials for Degenerative Disc Disease

Clinical and Radiological Outcomes of Oblique Lateral Lumbar Interbody Fusion

Start date: January 1, 2013
Phase:
Study type: Observational

This study is undertaken to evaluate the outcomes of Oblique Lateral Lumbar Interbody Fusion (OLLIF). Specifically, the study seeks to measure outcomes on radiological imaging, outcomes reported by the patients on standardized questionnaires, and complication rates.