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Intervertebral Disc Degeneration clinical trials

View clinical trials related to Intervertebral Disc Degeneration.

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NCT ID: NCT06029764 Recruiting - Clinical trials for Adjacent Segment Degeneration

Extended One-level Interbody Fusion for Adjacent Vacuum Phenomenon in Lumbar Degenerative Disc Disease

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The main objective of this study was to validate the clinical effectiveness of interbody fusion with a one-segment extension for the treatment of adjacent segmental space discs in the surgical treatment of lumbar degeneration.

NCT ID: NCT06025175 Not yet recruiting - Disc Degeneration Clinical Trials

Low Level Lazer Therapy Effect on Vertebral Artery Blood Flow in Elderly With Cervical Disc Degeneration

Start date: September 15, 2023
Phase: N/A
Study type: Interventional

This study will include 60 elderly patients with cervical disc degeneration, from both gender who are aged from 60 - 75 years old.

NCT ID: NCT06011551 Not yet recruiting - Clinical trials for Degenerative Disc Disease (DDD)

HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs

HYDRAFIL-D
Start date: July 2024
Phase: N/A
Study type: Interventional

A multi-center, prospective, dual arm, randomized, controlled pivotal study to evaluate the safety and effectiveness of the ReGelTec HYDRAFIL™ System.

NCT ID: NCT06000319 Not yet recruiting - Clinical trials for Degenerative Disc Disease

Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion

Start date: September 2023
Phase:
Study type: Observational

The aim of this study is to evaluate the effectiveness and safety of Natural Matrix Protein™ (NMP™) fibers when used in cervical or lumbar interbody fusion in patients with degenerative disc disease (DDD), spinal stenosis, spondylolisthesis undergoing cervical or lumbar interbody spine fusion at no more than 3 adjacent levels.

NCT ID: NCT05997121 Recruiting - Clinical trials for Intervertebral Disc Degeneration

Safety and Performance of the Hexanium TLIF System in the Treatment of Degenerative Disc Disease

TLIF
Start date: July 9, 2021
Phase:
Study type: Observational

The goal of this observational study is to confirm the safety and efficacy of the Hexanium TLIF system in the treatment of skeletally mature patients suffering from degenerative disc disease (disease that occurs when the spinal disk break down). Part of their standard of care, participants will be questioned on their back and leg pains, their disability and if they have encountered any adverse effects since the Hexanium TLIF system implant surgery. Those data will be collected up to twenty four (24) months after the Hexanium TLIF system implant surgery.

NCT ID: NCT05976516 Recruiting - Cytokine Clinical Trials

CXCL2/CXCL8 Promote Intervertebral Disc Degeneration

Start date: August 1, 2023
Phase:
Study type: Observational

Low back pain (LBP) is the largest cause of morbidity in the world, and about 80% of Chinese people are affected in their lifetime. Although the prevalence of IDD gradually increases with age, IDD is very common among subjects under 30 years old. In addition to age, there are other factors, such as excessive or uneven mechanical load, obesity, genetics, nutrition, trauma and gender. In addition, it is not clear whether the heavy physical load associated with occupation is an important risk factor for IDD. Some studies have found that IDD is more common among athletes than the general population. Due to the complexity and multifactorial nature of IDD, its pathogenesis and risk factors are still unclear, which seriously hinders the rational stratification of LBP patients and limits the development of personalized treatment.

NCT ID: NCT05972616 Enrolling by invitation - Clinical trials for Degenerative Disc Disease

Natural Matrix Protein™ (NMP™) in Interbody Lumbar Fusion

Start date: August 2023
Phase:
Study type: Observational

The objective of this study is to evaluate the performance of Induce Biologics NMP™ when used to promote interbody fusion for degenerative disease of the lumbar spine.

NCT ID: NCT05971329 Not yet recruiting - Disc Degeneration Clinical Trials

Pilot Study of ZetaFuse™ Bone Graft for the Treatment of Cervical Degenerative Disc Disease

Start date: September 2024
Phase: Early Phase 1
Study type: Interventional

The goal of this pilot clinical trial is to test the safety and preliminary performance of the ZetaFuse Bone Graft in patient requiring fusion of the C3-C7 vertebral bones due to pain or loss of neurological function. Participants will be treated with ZetaFuse during surgical intervention to reduce pain and the loss of neurological function.

NCT ID: NCT05944081 Enrolling by invitation - Clinical trials for Degenerative Disc Disease

Postmarket Clinical Follow-Up Study on Arcadius XP L® Interbody Fusion Device

ARREST
Start date: March 15, 2024
Phase:
Study type: Observational

The purpose of this study is to collect clinical and radiological mid-term (min. 1 year) data on the ArcadiusXP L® lumbar stand-alone cage in a post-market clinical follow-up study (PMCF) limited to 60 patients.

NCT ID: NCT05883436 Recruiting - Clinical trials for Degenerative Disc Disease

Investigation of DEXA-C Anterior Cervical Interbody System

DEXA-C
Start date: February 22, 2023
Phase: N/A
Study type: Interventional

FDA Cleared interbody product for the cervical spine, designed to match a patients DEXA scan for increase in fusion rate.