Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome

Insulin Resistance Clinical Trial

— WBV  

Official title:

Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05215223
• Other study ID #: P.T.REC/012/003460
• Status: Completed
• Phase: N/A
• Start date: March 30, 2022
• Est. completion date: October 10, 2023

Study information

• Verified date: October 2023
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to investigate the effect of whole body vibration on insulin resistance in females with polycystic ovarian syndrome

Description:

polycystic ovarian syndrome is a complex endocrine condition characterized by metabolic abnormalities such as insulin resistance, excess weight or obesity, diabetes, and an increased risk of cardiovascular disease.Despite previous studies reported that physical exercise improves insulin resistance in females with polycystic ovarian syndrome, there is no study yet investigate the effect of whole body vibration on insulin resistance

Recruitment information / eligibility

• Status: Completed
• Enrollment: 46
• Est. completion date: October 10, 2023
• Est. primary completion date: October 1, 2023
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years to 35 Years

Eligibility

Inclusion Criteria:

1. Females with polycystic ovarian syndrome.

2. Their ages will range from 20 to 35 years.

Exclusion Criteria:

• 1-Smoking. 2-History of chronic disease.

Related Conditions & MeSH terms

• Insulin Resistance
• Polycystic Ovarian Syndrome
• Polycystic Ovary Syndrome
• Syndrome

Intervention

Device:
• whole body vibration
the patients will stand on whole body vibration device with maintaining squatting position while keeping their trunk extended. The first training session will be consisted of three sets of 1 min and will be separated by a 1-min of standing rest. intensity will 1 mm. Then one set will be added every session
• Treadmill
Females will be asked to perform moderate intensity aerobic exercise for 45 minutes for 3 times per week for 8 weeks

Locations

Country	Name	City	State
Egypt	Faculty of physical therapy	Giza

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Homeostasis Model Assessment (HOMA-IR)	Estimate insulin resistance (IR), it will be calculated according to the formula: fasting insulin (microU/L) x fasting glucose (nmol/L)/22.5.	eight weeks
Secondary	Waist circumference	by a tape measurement around the waist	eight weeks
Secondary	waist hip ratio	The formula = waist circumference / hip circumference.	eight weeks
Secondary	LH/FSH ratio	To assess the severity of PCOS	Eight weeks