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Insomnia clinical trials

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NCT ID: NCT00723970 Completed - Clinical trials for Major Depressive Disorder

Quetiapine Extended Release (XR) for the Treatment of Menopausal Depression

Start date: June 2007
Phase: Phase 4
Study type: Interventional

The study was designed to examine the efficacy and tolerability of quetiapine XR for the treatment of women who suffer from depression in the context of the menopausal transition and postmenopausal years. Besides the improvement of depressive symptoms, the investigators are interested in examining the impact of this medication on vasomotor symptoms (hot flashes, night sweats), sleep and overall quality of life.

NCT ID: NCT00723580 Completed - Insomnia Clinical Trials

Actigraphic Analysis of Treatment Response

Start date: May 2008
Phase: N/A
Study type: Interventional

The study examines and illustrates the utility of utilizing actigraphic measurements to assess treatment response.

NCT ID: NCT00722306 Completed - Insomnia Clinical Trials

A Study To Investigate The Absorption, Metabolism And Excretion Of [14C] PD 0200390 In Six Healthy Male Volunteers

Start date: May 2008
Phase: Phase 1
Study type: Interventional

To determine the mass balance of PD 0200390

NCT ID: NCT00716872 Completed - Cancer Clinical Trials

Improving the Sleep of Cancer Patients Using an Internet-Based Program

SHUTi-C
Start date: July 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether an Internet-based program, Sleep Healthy Using the Internet (SHUTi, or "Shut-Eye"), can help to improve the sleep of people who are in remission from cancer and experiencing symptoms of insomnia.

NCT ID: NCT00688025 Completed - Insomnia Clinical Trials

Magnetoencephalographic (MEG) Localization of Ramelteon's Effects on Brain Function and Cortical Arousal in Insomnia

Start date: May 2008
Phase: N/A
Study type: Observational

The present protocol will utilize simultaneous recording of brain activity during attention and memory tasks in insomnia participants after ramelteon vs. zolpidem vs. placebo administration. The investigators hypothesize that amplitudes of associated with memory will be unchanged by ramelteon, whereas zolpidem will significantly reduce brain activity associated with stimulus processing as evidenced by abnormal reduction in the amplitude of specific brain regions relative to placebo.

NCT ID: NCT00674830 Completed - Insomnia Clinical Trials

Self-help Treatment for Insomnia in Breast Cancer Patients

Start date: April 2008
Phase: N/A
Study type: Interventional

The main goal of this population-based study is to assess the efficacy of two forms of cognitive-behavioral therapy (CBT) to treat various levels of insomnia symptoms in women with breast cancer: a professionally administered form and a patient self-administered form. It is hypothesized that the two treatment conditions will be associated with significantly greater improvements in sleep, psychological distress, fatigue, cognitive functioning, and quality of life, relative to the control condition (i.e., usual care). It is also hypothesized that the magnitude of effect sizes obtained in association with treatment at each time assessment will be greater for the professionally administered treatment than the self-administered treatment.

NCT ID: NCT00666796 Completed - Insomnia Clinical Trials

A Study to Assess the Pharmacodynamic Interaction Between Gabapentin and Ethanol in Healthy Subjects

Start date: April 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the pharmacodynamic interaction between gabapentin and ethanol

NCT ID: NCT00656994 Completed - Insomnia Clinical Trials

Long-Term Efficacy of Ramelteon on Endocrine Function in Adult Subjects With Chronic Insomnia

Start date: January 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the long-term effects of Ramelteon, once daily (QD), on endocrine function values.

NCT ID: NCT00653562 Completed - Insomnia Clinical Trials

Zolpidem (Myslee) Post Marketing Study in Adolescent Patients With Insomnia - Evaluation With Polysomnography

Start date: November 2006
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy of zolpidem for adolescent insomniacs with polysomnography

NCT ID: NCT00645944 Completed - Schizophrenia Clinical Trials

Randomized, Controlled, Double Blind Trial of Eszopiclone for Insomnia Associated With Schizophrenia

Start date: April 2008
Phase: N/A
Study type: Interventional

The major goal of this project is to investigate established insomnia treatments in a schizophrenia population to see if the improved sleep leads to overall better quality of life. In addition, we hypothesize that the insomnia treatment may also lead to observed improvements in other symptoms associated with schizophrenia such as cognitive impairments, obesity, and negative symptoms.