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Insomnia clinical trials

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NCT ID: NCT02314624 Completed - Depression Clinical Trials

PracticeGround: Transforming Training and Delivery of Mental Health EBPs

Start date: December 2014
Phase: N/A
Study type: Interventional

The ultimate goal is to facilitate the delivery of empirically supported treatments (ESTs) for mental disorders and to improve client mental health outcomes. Toward this end, this Phase II SBIR proposal seeks to complete the development and testing of PracticeGround, a comprehensive software system designed to integrate with electronic health records, and that contains multiple methods of training clinicians in ESTs and delivering ESTs to clients, continuous progress monitoring of client outcomes, and clinical support tools to guide clinicians and clients through delivery of the necessary EST. The investigators will conduct an 18-week randomized controlled trial (N=80) comparing PracticeGround (n=40) to care-as-usual (n=40) in depressed outpatient clients. PracticeGround clinicians will have full access to the software. Study clinicians and clients will be assessed once every six weeks (baseline, 6, 12, and 18 weeks). To ensure generalizability of findings, the investigators will not control for natural therapy variations (e.g.,session frequency, medication use, etc.). Primary outcomes include: depression, psychological distress, treatment satisfaction (clients and clinicians), and treatment drop out. Secondary clinician outcomes include: extent of PracticeGround use with clients across clinicians' caseload.

NCT ID: NCT02299193 Completed - Hypertension Clinical Trials

Online CBT-I for High Blood Pressure

Start date: August 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect of 6-weekly, 20 minute sessions of 2 online behavioral sleep interventions (cognitive behavioral therapy or healthy sleep habits) on blood pressure, sleep, depressive symptoms and anxiety in people with insomnia and prehypertension or hypertension.

NCT ID: NCT02295345 Completed - Insomnia Clinical Trials

Open Pilot of Cognitive Behavioural Therapy for Insomnia in Pregnancy

Start date: June 2014
Phase: N/A
Study type: Interventional

Despite the literature showing cognitive behavioural therapy for insomnia (CBT-I) to be effective in a variety of populations including postpartum women, as well as the demonstrated harmful consequences of sleep disturbances in late pregnancy, no trials have investigated its efficacy during pregnancy. This project will investigate the efficacy and acceptability of cognitive behavioral therapy for insomnia (CBT-I) in pregnancy.

NCT ID: NCT02290496 Completed - Depression Clinical Trials

CBT Insomnia Teens: Augmenting SSRIs to Improve Youth Depression

SleepWell
Start date: March 2015
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial that tests the effectiveness of cognitive behavior therapy (CBT) for insomnia with comorbid depression in youth aged 12 through 19 who have recently begun selective serotonin re-uptake inhibitor (SSRI) antidepressants. CBT is compared with a control condition of sleep hygiene education.

NCT ID: NCT02290405 Completed - Insomnia Clinical Trials

Impact of Hyperarousal on Simple and Complex Cognitive Task Performance Among Insomnia Sufferers

Start date: October 1, 2014
Phase:
Study type: Observational

The purpose of this study is to learn more about people with insomnia disorder and cognitive impairment. Cognitive impairment is difficulty with mental abilities such as thinking, knowing and remembering.

NCT ID: NCT02279056 Completed - Insomnia Clinical Trials

Randomized Controlled Trial of a Self-help Book for Insomnia in Patients With Co-morbid OSA and Insomnia

Start date: October 2014
Phase: N/A
Study type: Interventional

Obstructive sleep apnea (OSA) is a common sleep disorder treated with continuous positive airway pressure (CPAP). Some OSA patients also suffer from co-morbid insomnia. CPAP treatment may be complicated in patients with co-morbid insomnia. This project evaluates the effects of a self-help book for insomnia in patients being treated with CPAP for OSA.

NCT ID: NCT02268565 Completed - Insomnia Clinical Trials

Preventing the Inflammatory Response to Experimentally-induced Insomnia Symptoms

Start date: October 2014
Phase: Early Phase 1
Study type: Interventional

The main purpose of this study is to learn about the effects of sleep disruption (two days in a row where sleep is shortened and disrupted) on inflammation, mood (how you feel), and pain processing (your own experiences/perceptions of pain). In this research project, we are trying to figure out if we can change the effects of sleep disruption on inflammation, mood, and pain. Therefore, we will study whether taking a low-dose aspirin pill every day over 2 weeks can change how we respond to sleep disruption. For example, does the sensitivity to pain (e.g., how intense the feeling of pain is if we put our hand in very hot or very cold water) change with sleep disruption, and can low-dose aspirin influence this change. We are also interested in seeing how inflammation changes in relation to your own perceived experience of pain.

NCT ID: NCT02261597 Completed - Insomnia Clinical Trials

Challenging the Inflammatory Response System in Insomnia Disorder

Start date: January 2015
Phase:
Study type: Observational

The main purpose of this study is to understand how insomnia (compared to good sleep) may affect the response of the body to a repeated physiological challenge, such as inserting the hand in ice-cold water for several times in a row. In particular, the investigators are interested in the response of markers that can be associated with stress, such as blood pressure and stress hormones.

NCT ID: NCT02260843 Completed - Insomnia Clinical Trials

Efficacy of Tai Chi Training on Insomnia in Older Adults

Start date: August 2014
Phase: N/A
Study type: Interventional

Elderly insomnia is a serious public health problem. Current conventional approaches for treating insomnia are not suitable or effective in elderly population. It has been previously demonstrated that Tai Chi has definite advantages to be developed as self-help therapy in older adults and has been preliminarily demonstrated to improve sleep in older people. This project aims to evaluate the efficacy of Tai Chi training on alleviating chronic insomnia in older adults.

NCT ID: NCT02259101 Completed - HIV Clinical Trials

RCT of CBT for Insomnia With PLWHA

Start date: November 2013
Phase: N/A
Study type: Interventional

The proposed study will consist of a randomized controlled trial (RCT) comparing a known efficacious treatment for insomnia (CBT-I) to a sleep hygiene (SH) comparison condition.