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Inhalation Injury clinical trials

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NCT ID: NCT06326593 Recruiting - Inhalation Injury Clinical Trials

Wii Aerobic Training in Inhalation-injury Children Post-thermal Burn

Start date: February 22, 2024
Phase: N/A
Study type: Interventional

Inhalation injury is a composite of multiple insults including: supra glottic thermal injury, subglottic airway and alveolar poisoning, and systemic poisoning from absorbed small molecule toxins. These contaminant insults independently affect each of the pulmonary functions as well as having a direct effect on systemic physiology. Further, anatomic characteristics can predispose patients to inhalation injury. For example, an infant will develop airway obstructions much faster than an adult due to reduced airway diameter. Understanding the contributions of each of these pathologies to the patient's disease is critical to managing inhalation injury. Wii fit aerobic training gives similar results with traditional rehabilitation practices, it causes less energy costs. This suggests that it can be a suitable rehabilitation tool for adult and elderly people with low energy levels. A review showed that video games are safe and feasible in the children with lung complications. Children' balance, aerobic and cognitive functions, quality of life improved and depressive mood decreased. WII aerobic games also make children to communicate better with other family members.

NCT ID: NCT05988294 Recruiting - Inhalation Injury Clinical Trials

Pilates Exercises in Patients With Inhalation Injury

Start date: July 30, 2023
Phase: N/A
Study type: Interventional

Inhalation injury is a composite of multiple insults including: supraglottic thermal injury, subglottic airway and alveolar poisoning, and systemic poisoning from absorbed small molecule toxins. These contaminant insults independently affect each of the pulmonary functions as well as having a direct effect on systemic physiology. Further, anatomic characteristics can predispose patients to inhalation injury. For example, an infant will develop airway obstructions much faster than an adult due to reduced airway diameter. Understanding the contributions of each of these pathologies to the patient's disease is critical to managing inhalation injury.

NCT ID: NCT05915494 Recruiting - Inhalation Injury Clinical Trials

Intermittent-pneumatic Compression in Inhalation-injury Children: Effects on Diaphragm Mobility and Pulmonary Function

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

inhalation injury is very common in infants, young, children. complications of this problems are low pulmonary functions and limited mobility of main inspiratory muscle.

NCT ID: NCT05886543 Completed - Inhalation Injury Clinical Trials

Pilates Exercise and Inhalation Injury Post Burn

burn
Start date: September 30, 2021
Phase: N/A
Study type: Interventional

Sixty patients with 25-45 years of age presenting post burn inhalation injury, randomly distributed into two equal groups, 30 patients for each group. control group receive conventional chest physiotherapy (diaphragmatic respiratory exercises, apical breathing exercises) for (15-20) minutes 3times/week and medical treatment for 4 weeks as a total period of treatment. study group will receive pilates exercise in addition to their conventional chest physiotherapy for (15-20) minutes 3times/week and medical treatment for 4 weeks as a total period of treatment, computerized spirometer assessment before treatment are ( The following variables were measured: forced vital capacity (PVC%) and forced ·expiratory volume in one second (FEVl %) and peak expiratory flow (PEF %)and after one month

NCT ID: NCT05718830 Completed - Inhalation Injury Clinical Trials

Selecting Specific Bio-markers and Researching Mechanisms of Immune Regulation From Inhalation Injury and Traumatic Lung Injury Based on Single Cell Sequencing Technology

Start date: January 1, 2021
Phase:
Study type: Observational

The goal of this observational study is to profile the circulating immunological traits of patients with traumatic lung injury (TLI) and inhalation injury (ILI),providing a new direction for the depth research of the pathogenesis, and providing new immune-related targets for diagnosis of the severity of lung injury and treatment. The investigators performed scRNA-seq of neutrophil and peripheral blood mononuclear cells (PBMCs) from 10 ml fresh circulating blood from 3 patients with TLI and 3 patients with ILI at longitudinal timepoints,as well as peripheral blood from 3 health controls(HCs).

NCT ID: NCT05705713 Completed - Inhalation Injury Clinical Trials

First-day Computed Tomography: Does it Has a Role in the Assessment of Patients With Inhalation Lung Injury?

Start date: December 1, 2015
Phase: N/A
Study type: Interventional

A major risk factor for death in burn victims is inhalation lung injury. Diagnostic criteria and severity grading are not well understood. After an inhalation injury, the mucociliary escalator is impaired by induced mucosal hyperemia, which includes Edema, increased mucous production, and airway exudation, and these insults worsen airway narrowing which interferes with ventilation. Multimodal therapy and quick bronchoscopic diagnosis improve patient outcomes. Early identification and classification of inhalation injuries improve patient outcomes. Chest CT may be employed as an alternative to or supplement to the bronchoscopy as well as a diagnostic and prognostic tool. In this study, the diagnostic and prognostic value of bronchial wall thickening as a radiological CT finding in inhalation lung damage and the radiologist score (RADS) were evaluated.

NCT ID: NCT05190497 Recruiting - Pulmonary Function Clinical Trials

Effects of IMT on Pulmonary Functions IN CASES With Inhalation Injury

Start date: November 30, 2021
Phase: N/A
Study type: Interventional

The current study aimed to investigate the effect of inspiratory muscle training (IMT) on pulmonary functions (FEV1and FVC), and respiratory muscle strength in patients with inhalation injury, which may prove to be a promising intervention helping to improve exercise tolerance, relieve dyspnea and suggests an improvement in respiratory muscle function.

NCT ID: NCT04667676 Completed - Inhalation Injury Clinical Trials

Respiratory Functions Response To Tens Acupoint Stimulation Post Inhalation Injury

Start date: June 10, 2018
Phase: N/A
Study type: Interventional

this study designed to examine the effect of Acu-TENS applied bilaterally on Ding Chuan acupoint to boost pulmonary functions, improve diaphragmatic excursion and decrease dyspnea in patients with inhalation injuries.

NCT ID: NCT04125108 Completed - Pulmonary Disease Clinical Trials

The Effect of a Pulmonary Rehabilitation on Lung Function and Exercise Capacity in Patients With Burn

Start date: October 10, 2019
Phase: N/A
Study type: Interventional

Inhalation burn injury and lung complications caused by large surface burns occurring during a fire remains a serious problem. Pulmonary rehabilitation has been used successfully to improve pulmonary function(PF) in patients with chronic obstructive pulmonary disease. But there were no studies that pulmonary rehabilitation induce improvements in PF in patient with large surface burn and inhalation injury. The investigators will performe pulmonary function and respiratory muscles strength evaluation in 40 patients with thermal injury in order to evaluate the effects of pulmonary rehabilitation in patients with thermally injury.

NCT ID: NCT01773083 Terminated - Burn Injury Clinical Trials

Trial of Nebulized Heparin Versus Placebo for Inhalation Trauma

Hepburn
Start date: October 2013
Phase: Phase 3
Study type: Interventional

The purpose of this international multi-center double-blind randomized placebo-controlled trial is to determine the effect of nebulized heparin, compared to placebo, on the number of ventilator-free days at day 28, in burn patients with confirmed inhalation trauma requiring mechanical ventilation.