Influenza Clinical Trial
Official title:
Zoonotic Influenza Infections of Swine Origin at Ohio Agricultural Fairs
Verified date | June 17, 2019 |
Source | National Institutes of Health Clinical Center (CC) |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Background:
- The flu is a very infectious and contagious virus that affects both people and pigs.
Studies show that pigs can be sources of the flu virus in humans. Researchers want to know
more about how the flu is transmitted from animals to people. If they know more about it,
they can find better ways to prevent the flu and treat people who get sick from it.
Objective:
- To discover if flu viruses can be found in people exposed to pigs at Ohio agricultural
fairs.
Eligibility:
- Volunteers 8 years of age and older who exhibit pigs at Ohio agricultural fairs.
Design:
- Before or on the first day of the fair, participants will fill out a short demographic
and medical history form. They will also complete a two-page symptom questionnaire. This
is a form that asks them about any flu symptoms they might have.
- Participants will have a nasal swab performed. The inside of the participant s nose will
be rubbed with a swab to collect nasal fluid.
- Researchers will see participants 2 days later and 4 days later. During these visits,
participants will again fill out a symptom questionnaire and have a nasal swab.
Status | Completed |
Enrollment | 336 |
Est. completion date | June 17, 2019 |
Est. primary completion date | June 17, 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 8 Years and older |
Eligibility |
- INCLUSION CRITERIA: - Volunteers greater than or equal to 8 years of age - Parental consent if a participant is less than 18 years of age - Willing to have samples stored for future research - Willingness to complete all study procedures - Daily or nearly daily contact with swine during selected agricultural fairs EXCLUSION CRITERIA: Any medical condition or circumstance that may make it unsafe for the participant to have nasal swab performed. |
Country | Name | City | State |
---|---|---|---|
United States | Ohio State University, College of Veterinary Medicine | Columbus | Ohio |
Lead Sponsor | Collaborator |
---|---|
National Institute of Allergy and Infectious Diseases (NIAID) | Ohio State University |
United States,
Gray GC, McCarthy T, Capuano AW, Setterquist SF, Olsen CW, Alavanja MC. Swine workers and swine influenza virus infections. Emerg Infect Dis. 2007 Dec;13(12):1871-8. doi: 10.3201/eid1312.061323. — View Citation
Reid AH, Taubenberger JK. The origin of the 1918 pandemic influenza virus: a continuing enigma. J Gen Virol. 2003 Sep;84(Pt 9):2285-92. Review. — View Citation
Webster RG. The importance of animal influenza for human disease. Vaccine. 2002 May 15;20 Suppl 2:S16-20. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Identification of influenza A virus infections occurring due to swinevariant influenza | Ongoing |
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