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Influenza clinical trials

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NCT ID: NCT00867139 Completed - Influenza Clinical Trials

TCAD vs. Monotherapy for Influenza A in Immunocompromised Patients

Start date: March 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of triple combination antiviral drug (TCAD) for use in immunocompromised patients with Influenza A infection, and to gain data on the effectiveness of TCAD

NCT ID: NCT00866580 Withdrawn - Influenza Clinical Trials

A Study for Evaluation of GSK Biologicals' Pandemic Influenza Vaccine

Start date: May 2010
Phase: Phase 3
Study type: Interventional

This observer-blind study is designed to evaluate the immune response and safety of pandemic influenza vaccine in the elderly population.

NCT ID: NCT00858468 Completed - Influenza Clinical Trials

Safety and Immunogenicity Testing of Influenza Vaccine in Healthy Children 2 Months and 6 Months of Age

Start date: April 2005
Phase: Phase 1/Phase 2
Study type: Interventional

Primary Objective: To describe the safety of the 2004-2005 pediatric formulation of the inactivated, split-virion influenza vaccine Fluzone®, given in the two-dose schedule (described in the package insert for vaccine-naïve young children) to the investigational and control groups. Observational Objective: To describe the percentage of protective Hemagglutination Inhibition (HAI) antibody titers (following a 2-dose Fluzone® immunization series) to each of the 3 vaccine antigens among the investigational and control groups.

NCT ID: NCT00853255 Completed - Influenza Clinical Trials

Group Study of the Safety of and Immune Response to a Single Dose of Bird Flu Vaccine (H7N3) in Healthy Adults

Start date: July 2010
Phase: Phase 1
Study type: Interventional

Over the past decade, avian influenza (AI) has become a major health concern. The development of safe and effective vaccines against avian strains that infect people is important. The purpose of this study is to determine the safety of and immune response of an investigational AI vaccine in healthy adults against the H7N3 strain of avian influenza.

NCT ID: NCT00851266 Completed - Influenza Clinical Trials

A Study of a Bivalent Influenza Peptide Conjugate Vaccine in Healthy Adults

Start date: October 2006
Phase: Phase 1
Study type: Interventional

This is a first in man study evaluating the tolerability and immunogenicity of BIPCV/IMX (V512) at increasing concentrations of influenza viral peptides A/M2+B/HA0 peptides and IMX, a saponin-based adjuvant.

NCT ID: NCT00848887 Completed - Influenza Clinical Trials

A Dose Ranging Study Comparing Different Combinations of Adjuvanted and Non-adjuvanted Influenza Vaccines in Healthy Children 6 to <36 Months of Age

Start date: October 2008
Phase: Phase 1
Study type: Interventional

This study will evaluate the safety and immunogenicity of different combinations of influenza vaccine in healthy young children.

NCT ID: NCT00848848 Completed - Influenza Clinical Trials

Safety, Tolerability, and Immunogenicity of Different Combinations of Trivalent Influenza Vaccine Varying Influenza Antigen Dose, Adjuvant Dose, and Route of Administration in Healthy Elderly Individuals Ages 65 Years and Older

Start date: October 2008
Phase: Phase 1
Study type: Interventional

The study will evaluate the safety, tolerability and immunogenicity of different doses and types of Influenza Vaccine in healthy elderly subjects.

NCT ID: NCT00845429 Completed - Influenza Clinical Trials

Immunogenicity of a Split, Cell-Based, Inactivated, Trivalent Influenza Vaccine in Healthy Adult Subjects

Start date: October 2007
Phase: Phase 2
Study type: Interventional

Primary Objective: To describe the immune response to a single administration of 2 formulations of the investigational cell-based influenza vaccines in healthy adult subjects. Secondary Objective: To describe the safety following a single administration of 2 formulations of the investigational cell-based influenza vaccines in healthy adult subjects.

NCT ID: NCT00844051 Completed - Influenza Clinical Trials

Study to Evaluate Impact of School-based Influenza Vaccination on School Populations

Start date: January 2009
Phase: N/A
Study type: Interventional

Rates of confirmed influenza illness in vaccinated and non-vaccinated children will be compared between schools with and without vaccination programs. The investigators hypothesize that in addition to lowering rates of influenza in vaccinated children, raising vaccination rates by 30-40% through school-based vaccination programs will decrease incidence of influenza in non-vaccinated children attending those schools compared to non-vaccinated children in schools with low vaccination rates.

NCT ID: NCT00836953 Completed - Influenza Clinical Trials

Study to Collect Sera for Immunogenicity Testing in Children Vaccinated With Fluzone®

Start date: September 2003
Phase: Phase 4
Study type: Interventional

To describe the safety findings from Days 0 to 44 following injection of the 2003-2004 pediatric formulation of the inactivated, split-virion influenza vaccine Fluzone®, given in the two-dose schedule in accordance with the Package Insert, in children aged ≥ 6 months to < 36 months. To describe the immunogenicity findings from Days 0 to 44 following injection of the 2003-2004 pediatric formulation of the inactivated, split-virion influenza vaccine Fluzone®, given in the two-dose schedule in accordance with the Package Insert, in children aged ≥ 6 months to < 36 months