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Influenza clinical trials

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NCT ID: NCT01306682 Completed - Influenza Clinical Trials

Influenza Vaccination of HIV Infected Pregnant Women: Safety and Immunogenicity

MatfluHIVpos
Start date: March 2011
Phase: Phase 2/Phase 3
Study type: Interventional

This randomized, placebo controlled trial will evaluate the safety and immunogenicity of Trivalent Influenza Vaccine (TIV) in HIV-infected pregnant women, dynamics of transplacental anti-influenza antibody transfer to their newborns and kinetics thereof during early infancy.

NCT ID: NCT01306669 Completed - Influenza Clinical Trials

Influenza Vaccine Trial in HIV Uninfected Pregnant Women

MatfluHIVneg
Start date: March 3, 2011
Phase: Phase 3
Study type: Interventional

Randomised, double blind, placebo controlled trial to assess safety, immunogenicity and efficacy of Trivalent Influenza vaccine in HIV uninfected pregnant women

NCT ID: NCT01306305 Completed - Influenza Clinical Trials

A Re-licensing Study to Assess the Efficacy of Inflexal V Formulated With WHO Recommended 2010/2011 Influenza Virus Strains for the Northern Hemisphere

Start date: June 2010
Phase: Phase 4
Study type: Interventional

A study to assess whether the Northern Hemisphere 2010/2011 season influenza vaccine Inflexal V fulfills the EMEA requirements for re-registration of influenza vaccines

NCT ID: NCT01306253 Completed - Influenza Clinical Trials

A Re-licensing Study to Assess the Efficacy of Inflexal V Formulated With WHO Recommended 2009/2010 Influenza Virus Strains for the Northern Hemisphere

Start date: June 2009
Phase: Phase 4
Study type: Interventional

This study is to assess whether the Northern Hemisphere 2009/2010 season influenza vaccine Inflexal V fulfills the EMEA requirements for re-registration of influenza vaccines.

NCT ID: NCT01304771 Completed - Influenza Clinical Trials

Safety of Synbiotics as Adjuvant to Influenza Vaccine in Elderly

Start date: December 2010
Phase: Phase 1
Study type: Interventional

Probiotics are viable commensal microorganisms that promote the establishment of beneficial microflora. Animal and human studies demonstrate that probiotics can enhance body's immune response to stimuli. Mayo Clinic in conjunction with Agri-King Corporation has developed a novel synbiotic called AKSB (Agri-King Synbiotic) that contains a probiotic bacterium (Enterococcus faecium, microencapsulated SF68 or Ventrux ME 30), a probiotic yeast (Saccharomyces cerevisiae, Lynside® Pro-Lay 1), and a prebiotic (fructo-oligosaccharide [FOS], NutraFlora®). This phase I placebo-controlled trial of AKSB in normal human volunteers, over 65 years of age, is designed to study the safety of this probiotic when patients are also receiving an influenza vaccine. If this study shows that AKSB is safe then our aim is to do a larger study to see if we can improve influenza vaccine immune response while taking the probiotic compared to placebo.

NCT ID: NCT01304563 Completed - Influenza Clinical Trials

2010/2011 Trivalent Influenza Vaccination

Start date: November 2010
Phase: N/A
Study type: Interventional

Intradermal influenza vaccination may result in better efficacy when compare to intramuscular vaccination.

NCT ID: NCT01303510 Completed - Influenza Clinical Trials

A Re-licensing Study to Assess the Efficacy of Inflexal V Formulated With WHO Recommended 2008/2009 Influenza Virus Strains for the Northern Hemisphere

Start date: July 2008
Phase: Phase 4
Study type: Interventional

A study to assess whether the Northern Hemisphere 2008/2009 season influenza vaccine Inflexal V fulfills the EMEA requirements for re-registration of influenza vaccines

NCT ID: NCT01299142 Recruiting - Influenza Clinical Trials

Safety and Pharmacokinetics Study of Human Monoclonal Antibody (FGI-101-1A6)

Start date: January 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety and tolerability of the anti-TSG101 human monoclonal antibody (FGI-101-1A6)when administered intravenously to healthy volunteers.

NCT ID: NCT01298102 Completed - Influenza Clinical Trials

Influenza A/H1N1/2009-adjuvanted Vaccine in Renal Disease Patients

Start date: October 2009
Phase: Phase 4
Study type: Interventional

In 2009, the pandemic influenza A/H1N1 accounted for worldwide recommendations about vaccination. There is no data concerning the immunogenicity nor the security of the adjuvanted-A/H1N1 vaccine in renal disease patients. The aim of this study is to observe the effects of this vaccine on transplanted and hemodialyzed patients.

NCT ID: NCT01286285 Enrolling by invitation - Influenza Clinical Trials

Surveillance of Influenza in Paediatric Intensive Care Units in Bavaria

Start date: October 2010
Phase: N/A
Study type: Observational

The purpose of the study is to assess the number of severe, laboratory-confirmed influenza in children hospitalized to paediatric intensive care units. Furthermore, the proportion of these children from all children hospitalized to paediatric intensive care units with acute respiratory infections will be established.