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Influenza clinical trials

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NCT ID: NCT00382187 Completed - Influenza Clinical Trials

Safety and Immunogenicity of Two Adjuvanted and One Non-adjuvanted H5N1 Influenza Vaccine in Adults

Start date: November 2006
Phase: Phase 2
Study type: Interventional

The present study aims to evaluate safety and immunogenicity of two doses, administered three weeks apart, and a 6 month booster dose, of two influenza vaccines containing 7.5 micrograms or 15 micrograms of H5N1 influenza antigen, and of a non-adjuvanted influenza vaccine containing 15 micrograms of H5N1 influenza antigen, in adults

NCT ID: NCT00380237 Completed - Influenza Clinical Trials

Safety of and Immune Response to a Bird Flu Virus Vaccine (H9N2) in Healthy Adults (Study B)

Start date: October 2006
Phase: Phase 1
Study type: Interventional

Avian influenza (AI), also known as bird flu, has become a major public health concern in many regions of the world. The purpose of this study is to evaluate the safety of and immune response to an AI vaccine in healthy adults.

NCT ID: NCT00380211 Completed - Influenza Clinical Trials

Safety and Immunogenicity of FluLaval™ TR and Fluarix® (Influenza Vaccines) in Young and Older Adults

Start date: September 2006
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to describe the immunogenicity, the safety, and tolerability of FluLaval™ TR and Fluarix®, the latter serving as active comparator. The results will be compared to a standard immune response criteria, for both young and elderly populations.

NCT ID: NCT00377611 Completed - Influenza Clinical Trials

Study on the Incidence of Influenza and Its Complications, in Subjects Aged 50 Years and Over Vaccinated With Fluarix™

Start date: October 5, 2006
Phase: Phase 4
Study type: Interventional

A study to investigate the incidence of influenza and influenza-related complications, in adults between 50-64 years and elderly adults 65 years and over vaccinated with Fluarix™

NCT ID: NCT00377585 Completed - Influenza Clinical Trials

Demonstrate the Superiority of the Immune Response of Adjuvanted Influenza Vaccine Induced in an Adult Population

Start date: September 22, 2006
Phase: Phase 2
Study type: Interventional

The study is designed to demonstrate a meaningful difference in immunogenicity between the candidate adjuvanted vaccine compared to the licensed Fluarix vaccine in subjects aged 50 years and above. A control group in younger adults aged 18 to 40 years was included.

NCT ID: NCT00376402 Completed - Influenza Clinical Trials

Study of a Pandemic Influenza Vaccine in Elderly Participants

Start date: October 2006
Phase: Phase 2
Study type: Interventional

The World Health Organisation has warned that an influenza pandemic is inevitable. The avian influenza H5N1 virus strain is one of the leading candidates to cause the next influenza pandemic. The elderly are likely to be a special target group for vaccination; therefore, this study will test the safety and immunogenicity of a H5N1 pandemic influenza vaccine in a healthy elderly population.

NCT ID: NCT00375206 Completed - Influenza Clinical Trials

A Safety and Immunology Study of a DNA Trivalent Influenza Vaccine

Start date: September 2006
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate how well the vaccine is tolerated at sites where administrations are given and any effects it may have on subjects' wellbeing. The study will also test the ability of vaccine to cause particular immune responses in the body.

NCT ID: NCT00375115 Completed - Influenza Clinical Trials

Efficacy of Sambucol in the Treatment of Influenza

Start date: September 2006
Phase: Phase 4
Study type: Interventional

The trial will examine the efficacy of sambucol in the treatment of influenza. The primary efficacy endpoint will be the length of time to resolution of influenza illness.The double blind trial will be conducted at the Personnel Clinic, and at the Clinical virology Unit, Hadassah University Hospital, and will include 100 patients with laboratory-confirmed influenza infection, 50 in the sambucol and 50 in the placebo study arm.

NCT ID: NCT00374842 Completed - Influenza Clinical Trials

Study to Evaluate the Immunogenicity and Safety of 2 Formulations of GlaxoSmithKline (GSK) Biologicals' GSK1247446A Low Dose Influenza Vaccine Candidate

Start date: October 3, 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the immunogenicity and the safety of candidate vaccines compared to Fluarix™ administered intramuscularly in subjects aged 18-59 years

NCT ID: NCT00372255 Completed - Influenza Clinical Trials

Study on the Immunogenicity and Tolerability of Influsplit SSW® 2005/2006 in Children Aged 6 - 13 Years

Start date: November 17, 2005
Phase: Phase 4
Study type: Interventional

The study will evaluate the immune response and the tolerability of the influenza vaccine administered in children aged 6-13 years old.