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"System Medicine" Approach for Prevention Strategies for Comorbidities in Infertile Men

Infertility Clinical Trial

Official title:
New "System Medicine" Approach for the Development of Primary Prevention Strategies for Comorbidities in Infertile Men

Clinical Trial Summary

By applying a "system medicine" approach, the project aims to identify new biomarkers and/or prognostic tools aimed at developing personalized strategies to prevent the onset of comorbidities in infertile men.

Clinical Trial Description

By applying a "system medicine" approach, the project aims to identify new biomarkers and/or prognostic tools aimed at developing personalized strategies to prevent the onset of comorbidities in infertile men. The findings will provide new insights into the relationship between male infertility and somatic health, and shed light on the role of the microbiome in modulating the activity of the immune system. A "signature" of lack of immunological tolerance and biomarkers could be useful to predict future oncologic and non-oncological comorbidities in infertile men. This will let the development of a more clinically reliable and cost-effective personalized primary/secondary prevention strategy in a population at high risk of clinically relevant diseases. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06183255
Study type Observational
Source IRCCS San Raffaele
Contact Andrea Salonia, MD
Phone 02 2643 5661
Email salonia.andrea@hsr.it
Status Recruiting
Phase
Start date January 18, 2021
Completion date July 2025
View Details
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