Infertility Clinical Trial
Official title:
Studies Aiming at Identifying Predictors for Fertility Treatments' Outcomes and to Evaluate the Efficacy and Safety of Fertility Preservation
Verified date | May 2023 |
Source | Karolinska Institutet |
Contact | Dan Grandér, Prof |
dan.grander[@]ki.se | |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This study analyses clinical data prospectively collected for over a decade in several clinical databases. Electronic medical records are available since 1998. Since 2011 the subgroup of patients that undergo fertility preservation are invited to participate in a prospective study aiming at long-term follow-up after fertility preservation for oncologic and non-oncologic conditions.
Status | Recruiting |
Enrollment | 50000 |
Est. completion date | December 2030 |
Est. primary completion date | December 2028 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A to 56 Years |
Eligibility | Inclusion Criteria: - infertile patients and patients who undergo fertility preservation Exclusion Criteria: - Healthy individuals, fertile population |
Country | Name | City | State |
---|---|---|---|
Sweden | Reproductive Medicine, Karolinska University Hospital | Stockholm |
Lead Sponsor | Collaborator |
---|---|
Karolinska Institutet | Karolinska University Hospital |
Sweden,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Efficacy and safety of fertility preservation - Long-term follow-up | Correlation between method of fertility preservation and pregnacy rate | 2028 | |
Secondary | Clinical outcome of fertility treatments i breast cancer patients | Fertility treatment vs no fertility treatment i breastcancer patients: effect on survival | 5-20 years post diagnosis | |
Secondary | Clinical outcome of fertility treatments i breast cancer patients | Fertility treatment vs no fertility treatment i breastcancer patients: effect on disease free survival | 5-7 years post diagnosis | |
Secondary | Predictors of effictive fertility treatment | Correlation between clinical variables (age, BMI, oocyte level, administered gonadotropins, infertility) method of fertility preservation and Pregnancy rate | patient data collected from time of treatment, pregnancy rate until end of study | |
Secondary | Efficacy and safety of COS using GnRHa for fertility preservation in BC patients | hCG vs GnRH trigger on effect on number of cryopreserved embryos and oocytes | Observed outcomes in patients registered between 1995 and 2017. Follow up until end of 2018. |
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