Ultrasound Guidance for Embryo Transfer

Infertility Clinical Trial

Official title:

Transvaginal Versus Transabdominal Ultrasound Guided Embryo Transfer. Randomized Controlled Trial.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03851536
• Other study ID #: MU179
• Status: Completed
• Phase: N/A
• Start date: June 2, 2016
• Est. completion date: March 9, 2019

Study information

• Verified date: March 2019
• Source: Menoufia University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Randomized controlled study comparing the TVUS versus TAUS guidance during the procedure of embryo transfer.

Description:

The aim of this study was to Compare between transvaginal and transabdominal ultrasound guided embryo transfer as regarding clinical pregnancy rate, patient comfort, time required for embryo transfer and endometrial visualization at time of embryo transfer.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 178
• Est. completion date: March 9, 2019
• Est. primary completion date: February 15, 2019
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years to 42 Years

Eligibility

Inclusion Criteria:

All patients undergoing autologous ICSI and frozen embryo transfer (FET) cycles.

Exclusion Criteria:

1. Cases of sever ovarian hyperstimulation requiring embryo cryopreservation

2. Gestational surrogate cycles

3. Oocyte donation cycles

4. Very poor responders

5. Patients with inadequate visualization of the uterus by ultrasound.

6. Very difficult mock embryo transfer.

Related Conditions & MeSH terms

• Infertility

Intervention

Procedure:
• Transvaginal Ultrasound Guided ET
Use of TVUS to guide ET
• Transabdominal Ultrasound Guided ET
Use of TAUS to guide ET

Locations

Country	Name	City	State
Egypt	Alexandria University	Alexandria
Egypt	Menoufia University	Shibin Al Kawm	Monofiya

Sponsors (2)

Lead Sponsor	Collaborator
Menoufia University	Alexandria University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Clinical pregnancy	A clinical pregnancy is a pregnancy that is confirmed by ultrasonic visualization of gestational sac or heartbeat.	3 weeks after Embryo transfer
Secondary	Time required for ET	Time in seconds required for ET	Time from when the catheter is handed to the transferring physician to the time it is returned to the transferring embryologist.
Secondary	Degree of cramping and pain	Degree of cramping and pain from 0 to 10 by visual analogue scale (VAS) where 0 is no pain and 10 unbearable pain.	During and immediately after ET
Secondary	Endometrial visualization at time of embryo transfer	Endometrial visualization at time of embryo transfer by ultrasound	During ET