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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03678610
Other study ID # Ibnsina-ICSI-ionomycin-LA
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date September 25, 2018
Est. completion date May 1, 2019

Study information

Verified date May 2019
Source Ibn Sina Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Using Latrunculin A and Ionomycin would improve the outcome of ICSI if the handling medium during the ICSI procedure has them.


Recruitment information / eligibility

Status Completed
Enrollment 700
Est. completion date May 1, 2019
Est. primary completion date May 1, 2019
Accepts healthy volunteers No
Gender Female
Age group 18 Years to 42 Years
Eligibility Inclusion Criteria:

- indication for ICSI

Exclusion Criteria:

-

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Doing ICSI I a medium supplemented with Ionomycin and Latrunculin A
Ionomycin and Latrunculin A would activate oocyte during ICSI along with cytoskeleton stabilization for a favourable outcomes

Locations

Country Name City State
Egypt Banon Assiut Assiut
Egypt Qena Fertility Center Qena
Egypt IbnSina IVF Center Sohag

Sponsors (3)

Lead Sponsor Collaborator
Ibn Sina Hospital Banoon IVF Center, Qena Fertility Center

Country where clinical trial is conducted

Egypt, 

Outcome

Type Measure Description Time frame Safety issue
Primary Fertilization rate 6 days of culture
Secondary Rates of Blastocyst formation and quality Number of formed blastocysts and blastocysts with good-quality per fertilized oocytes 6 days of culture
Secondary embryo utilization rate 6 days of culture
Secondary clinical pregnancy rate three months
Secondary ongoing pregnancy rate 12 weeks
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