Cabergoline As An Adjuvant To Clomiphene Citrate For Management Of Unexplained Infertility

Infertility Clinical Trial

Official title:

Cabergoline As An Adjuvant To Clomiphene Citrate For Management Of Unexplained Infertility: Randomized Controlled Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03549741
• Other study ID #: CabCC
• Status: Not yet recruiting
• Phase: Phase 2/Phase 3
• Start date: July 2018
• Est. completion date: November 2019

Study information

• Verified date: May 2018
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Infertility refers to an inability to conceive after having regular unprotected sex. Infertility can also refer to the biological inability of an individual to contribute to conception, or to a female who cannot carry a pregnancy to full term. In many countries infertility refers to a couple that has failed to conceive after 12 months of regular sexual intercourse

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 120
• Est. completion date: November 2019
• Est. primary completion date: June 2019
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years to 35 Years

Eligibility

Inclusion Criteria:

• unexplained infertility, Primary or secondary.

• Absence of galactorrhoea.

• Normal serum prolactin.

• Normal hysterosalpingography.

• Normal spermogram.

Exclusion Criteria:

• Women on other line of treatment as aromatase inhibitors,gonadotrophins, or tamoxifen.

• Known hypersensitivity for cabergoline or clomiphene citrate.

• Other factors of infertility as tubal factor, uterine factor or male factor.

Related Conditions & MeSH terms

• Infertility

Intervention

Drug:
• Clomiphene Citrate 50mg
oral tablets
• Cabergoline Oral Tablet
oral tablets
• Placebo Oral Tablet
oral tablets

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The number of mature follicles	the follicles reach the size of 18 mm	14 days