The Impact of the Timing of Trigger on IVF Success

Infertility Clinical Trial

Official title:

The Impact of the Timing of Trigger on IVF Success: Randomized Control Trial

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT02990949
• Other study ID #: 20160397
• Status: Terminated
• Phase: N/A
• Start date: November 2016
• Est. completion date: June 15, 2022

Study information

• Verified date: October 2022
• Source: Colorado Center for Reproductive Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to examine the length of ovarian stimulation with the timing of trigger in an IVF cycle and its potential to impact patient outcomes.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 29
• Est. completion date: June 15, 2022
• Est. primary completion date: May 9, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 26 Years to 44 Years

Eligibility

Inclusion Criteria:

• Planning to move forward with an IVF cycle

• Have met the requirements of being a patient at CCRM Colorado

• AMA: 39-44 years old And/or

• DOR: AMH < 1 & FSH >10 (age independent)

Exclusion Criteria:

• Contraindication for pregnancy

• Have not fulfilled requirements for IVF cycle

• Single gene couple or chromosomal rearrangement

• Severe male factor or testicular surgical sperm removal (need sufficient sperm for ICSI)

• One ovary

• Uterine anomalies

• Stage III or IV endometriosis

• Explained recurrent miscarriage

• PCO or PCOS

• Using donor oocyte or gestational carrier

Related Conditions & MeSH terms

• Embryonic Development
• Fertilization in Vitro
• Infertility

Intervention

Other:
• Timing of trigger

Locations

Country	Name	City	State
United States	Colorado Center for Reproductive Medicine	Lone Tree	Colorado

Sponsors (2)

Lead Sponsor	Collaborator
Colorado Center for Reproductive Medicine	Fertility Laboratories Of Colorado

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Euploid Embryos: the percentage of euploid embryos produced as analyzed by comprehensive chromosomal screening, of total embryos tested		4 weeks after egg retrieval
Secondary	Egg maturation: the proportion of mature eggs of total number of eggs retrieved		1 week after egg retrieval
Secondary	Live birth outcomes: the incidence of pregnancy resulting in live birth following embryo transfer of embryos produced by this IVF cycle		9 months after frozen embryo transfer