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NCT02480491 Clinical Trial

Study of Free DNA Content of Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment

Infertility Clinical Trial

Official title:
Study of Cell Free DNA Content of Human Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment in ICSI Treatment Cycles

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02480491
Other study ID # SCS-1
Secondary ID
Status Completed
Phase N/A
First received June 20, 2015
Last updated June 23, 2015
Start date January 2014
Est. completion date May 2015

Study information
Verified date June 2015
Source Sadat City University
Contact n/a
Is FDA regulated No
Health authority Egypt: Genetic Engineering and Biotechnology Research Institute (GEBRI) Sadat City University
Study type Observational

Clinical Trial Summary

Study of Cell Free DNA Content of Human Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment in intra cytoplasmic sperm injection Treatment Cycles.

Description:

The aim of the present study is to determine whether cell free DNA content of the culture medium of the human embryo correlates with the quality and reproductive potential of embryos in ICSI cycles and, thus, to look for a new non invasive tool of assessing embryo quality beside morphological assessment. Determining a rapid, noninvasive method for the assessment of the developmental potential of embryos may be a great achievement

Recruitment information / eligibility
Status Completed
Enrollment 100
Est. completion date May 2015
Est. primary completion date February 2015
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group N/A and older
Eligibility Inclusion Criteria:

- third day embryos

Exclusion Criteria:

- less than third day embryos

Study Design

Observational Model: Cohort

Related Conditions & MeSH terms

Intervention

Other:
• measuring cell freeDNA
measuring cell free DNA using PCR

Locations
Country Name City State
n/a

Sponsors (2)
Lead Sponsor Collaborator
Sadat City University Ain Shams University

Outcome
Type Measure Description Time frame Safety issue
Primary correlations between levels of measured cell free DNA and embryo quality. 12 months No
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