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NCT02329197 Clinical Trial

Intrauterine Injection of Human Chorionic Gonadotropin Before Embryo Transfer in Women With Previous IVF Failure

Infertility Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT02329197
Other study ID # H005
Secondary ID
Status Recruiting
Phase Phase 4
First received December 26, 2014
Last updated December 30, 2014
Start date October 2014
Est. completion date March 2016

Study information
Verified date December 2014
Source Mansoura University
Contact Ahmed Gibreel, MD
Phone 002/01004045733
Email ahmedfathgi@yahoo.com
Is FDA regulated No
Health authority Egypt: Ministry of Higher Education
Study type Interventional

Clinical Trial Summary

Women with history of previous IVF cycle failure will be subjected to a fresh IVF cycle. At the time they will be undergoing embryo transfer, 50 IU of human chorionic gonadotropins diluted in 0.025ml of tissue culture media will be injected intrauterine by embryo transfer catheter 10 minutes before embryo transfer procedure.

Description:

Infertile women with history of previous IVF cycle failure will be subjected top a fresh IVF cycle. Following controlled ovarian hyperstimulation, ovum pick up and at the time they will be undergoing embryo transfer, 50 IU of human chorionic gonadotropins diluted in 0.025ml of tissue culture media will be injected intrauterine by embryo transfer catheter 10 minutes before embryo transfer procedure.

Recruitment information / eligibility
Status Recruiting
Enrollment 380
Est. completion date March 2016
Est. primary completion date October 2015
Accepts healthy volunteers No
Gender Female
Age group 19 Years to 40 Years
Eligibility Inclusion Criteria:

- women with previous IVF failure undergoing fresh IVF cycle

Exclusion Criteria:

- women with hydrosalpinges women with intrauterine lesion like submucous fibroid or polyps

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• Human Chorionic Gonadotropin (HCG)
intrauterine injection of HCG prior to embryo transfer in an IVF cycle

Locations
Country Name City State
Egypt Mansoura University Teaching Hospital Mansoura

Sponsors (1)
Lead Sponsor Collaborator
Mansoura University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Live Birth 9 months No
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