Infertility Clinical Trial
Official title:
The Influence of Different Concentrations of Glucose in Culture Media on In Vitro Fertilization Outcome of Sibling Oocytes
The importance of glucose in culture media on fertilization and embryo development is still controversial. Although it has been reported that glucose is essential for fertilization process and biosynthesis of membrane lipid and nucleic acids, comparatively high levels of glucose in culture media may cause developmental arrest of cleavage stage embryos. The aim of this retrospective study is to examine whether exposure of sibling oocytes to different concentrations of glucose in culture media has any further effect on IVF outcome.
Status | Not yet recruiting |
Enrollment | 600 |
Est. completion date | April 2016 |
Est. primary completion date | April 2016 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 42 Years |
Eligibility |
Inclusion Criteria: - Sibling oocytes from cycles where at least 4 oocytes were retrieved Exclusion Criteria: - Less than 4 oocytes retrieved - Partner has undergone testicular sperm extraction (TESE) |
Observational Model: Cohort, Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
Israel | Hillel Yaffe Medical Center | Hadera |
Lead Sponsor | Collaborator |
---|---|
Hillel Yaffe Medical Center |
Israel,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Fertilization Rate | Fertilization rates will be retrospectively compared according to culture media in which sibling oocytes were incubated | 2 years | No |
Secondary | Embryo Quality | Embryo quality and developmental rate will be retrospectively compared according to culture media in which sibling oocytes were incubated | 2 years | No |
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