Infertility Clinical Trial
Verified date | May 2015 |
Source | Rambam Health Care Campus |
Contact | n/a |
Is FDA regulated | No |
Health authority | Israel: Ministry of Health |
Study type | Interventional |
Ovulation trigger is needed in in vitro fertilization (IVF) to get mature eggs. Routinely,
human chorionic gonadotropin (hCG) is used for that purpose given its similarity to the
natural hormone that does this job in a natural cycle (luteinizing hormone, LH). In a
natural cycle another hormone takes part in the process (follicle stimulating hormone, FSH).
To induce a natural-like ovulation surge that includes LH and FSH , gonadotropin releasing
hormone (GnRH) agonist can be given.
The purpose of this study is to find out which approach may work better in IVF patients who
experienced 4 IVF failures.
Status | Completed |
Enrollment | 3 |
Est. completion date | April 2015 |
Est. primary completion date | January 2015 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 35 Years to 44 Years |
Eligibility |
Inclusion Criteria: - IVF patients with at least 4 consecutive failures. - On trigger day, no more than 10 follicles of 12 mm and up Exclusion Criteria: - History of moderate or severe OHSS. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Israel | IVF Unit, Rambam medical Center | Haifa |
Lead Sponsor | Collaborator |
---|---|
Rambam Health Care Campus |
Israel,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Fetal Heart Activity 1 Month After Oocyte Retrieval | Fetal heart activity as seen by vaginal ultrsound imaging 1 month after oocyte retrieval | 1 month after oocyte retrieval | No |
Secondary | Patients Comfort During the Luteal Phase | During 2 weeks from day of oocyte retrieval | No |
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