INFERTILITY Clinical Trial
Official title:
Evolutive Potential of Embryos Obtained From Oocytes After Luteal Phase Ovarian Stimulation
Verified date | March 2013 |
Source | Institut Universitari Dexeus |
Contact | n/a |
Is FDA regulated | No |
Health authority | Spain: Comité Ético de Investigación Clínica |
Study type | Interventional |
The purpose of this study is to evaluate the clinical pregnancy rate per embryo transfer in oocytes recipients obtained after ovarian stimulation during the luteal phase of oocytes donors . This study will be performed in egg recipients and donors but this type of treatment is meant to be implemented in fertility preservation patients
Status | Completed |
Enrollment | 15 |
Est. completion date | December 2013 |
Est. primary completion date | December 2013 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria: - premenopausal women, 18-35 years old, FSH levels < 10 mIU/ml; AFC> 10 - regular cycles - BMI < 28 - signed informed consent Recipients: - Infertile women eligible for oocytes donation - BMI < 35 - Signed informed consent form Exclusion Criteria: -Polycystic ovarian syndrome, gonadotropins allergy Recipients: - Women eligible for oocytes donation - BMI >35 - Uncontrolled Endocrine Pathology |
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Spain | Departamento de Obstetricia Ginecologia y Reproducción. Institut Universitari Dexeus | Barcelona |
Lead Sponsor | Collaborator |
---|---|
Institut Universitari Dexeus | Ayudas Merck Serono de Investigación 2012, FUNDACION DEXEUS SALUT DE LA DONA |
Spain,
Sönmezer M, Türkçüoglu I, Coskun U, Oktay K. Random-start controlled ovarian hyperstimulation for emergency fertility preservation in letrozole cycles. Fertil Steril. 2011 May;95(6):2125.e9-11. doi: 10.1016/j.fertnstert.2011.01.030. Epub 2011 Feb 3. — View Citation
von Wolff M, Thaler CJ, Frambach T, Zeeb C, Lawrenz B, Popovici RM, Strowitzki T. Ovarian stimulation to cryopreserve fertilized oocytes in cancer patients can be started in the luteal phase. Fertil Steril. 2009 Oct;92(4):1360-5. doi: 10.1016/j.fertnstert.2008.08.011. Epub 2008 Oct 18. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Pregnancy rate | six weeks after transfer procedure | No | |
Secondary | Number of Mature oocytes | Day of oocyte retrieval | No |
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